BRD-K58618158_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

63 genes differentially expressed following the BRD-K58618158_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8
ABHD4 abhydrolase domain containing 4
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ATP9A ATPase, class II, type 9A
C6ORF62 chromosome 6 open reading frame 62
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
GCH1 GTP cyclohydrolase 1
HMOX1 heme oxygenase 1
HSPH1 heat shock 105kDa/110kDa protein 1
IL10RA interleukin 10 receptor, alpha
KIF14 kinesin family member 14
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAOB monoamine oxidase B
MIR22HG MIR22 host gene
MPO myeloperoxidase
NAMPT nicotinamide phosphoribosyltransferase
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
PTX3 pentraxin 3, long
RBP4 retinol binding protein 4, plasma
RGCC regulator of cell cycle
S100A9 S100 calcium binding protein A9
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SGK1 serum/glucocorticoid regulated kinase 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SOD2 superoxide dismutase 2, mitochondrial
THBS2 thrombospondin 2
TXNRD1 thioredoxin reductase 1
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
ADGRE5 adhesion G protein-coupled receptor E5
ALCAM activated leukocyte cell adhesion molecule
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
CCND1 cyclin D1
CCNF cyclin F
CD24 CD24 molecule
CTBP2 C-terminal binding protein 2
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
GPRC5A G protein-coupled receptor, class C, group 5, member A
H1F0 H1 histone family, member 0
IGFBP3 insulin-like growth factor binding protein 3
KRT4 keratin 4, type II
LAMP5 lysosomal-associated membrane protein family, member 5
NRG1 neuregulin 1
PMEPA1 prostate transmembrane protein, androgen induced 1
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRSS23 protease, serine, 23
PSPH phosphoserine phosphatase
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RBM47 RNA binding motif protein 47
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RIPK4 receptor-interacting serine-threonine kinase 4
RPL31 ribosomal protein L31
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SPAG16 sperm associated antigen 16
SRC SRC proto-oncogene, non-receptor tyrosine kinase
TFF1 trefoil factor 1
TPM1 tropomyosin 1 (alpha)
TPM2 tropomyosin 2 (beta)
XPO7 exportin 7