BRD-K58347372_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

33 genes differentially expressed following the BRD-K58347372_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
CD24 CD24 molecule
CDH3 cadherin 3, type 1, P-cadherin (placental)
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
COL11A1 collagen, type XI, alpha 1
CRABP2 cellular retinoic acid binding protein 2
DDIT4 DNA-damage-inducible transcript 4
EGFL6 EGF-like-domain, multiple 6
HSPA1A heat shock 70kDa protein 1A
IL1R2 interleukin 1 receptor, type II
KRT15 keratin 15, type I
MYC v-myc avian myelocytomatosis viral oncogene homolog
PDXK pyridoxal (pyridoxine, vitamin B6) kinase
PRAME preferentially expressed antigen in melanoma
RCAN1 regulator of calcineurin 1
RGCC regulator of cell cycle
SFRP1 secreted frizzled-related protein 1
SFRP4 secreted frizzled-related protein 4
TIMP3 TIMP metallopeptidase inhibitor 3
TSC22D3 TSC22 domain family, member 3
VAT1 vesicle amine transport 1

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADIRF adipogenesis regulatory factor
C8ORF4 chromosome 8 open reading frame 4
CA2 carbonic anhydrase II
CASP7 caspase 7, apoptosis-related cysteine peptidase
CCNF cyclin F
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
GJA1 gap junction protein, alpha 1, 43kDa
IGHD immunoglobulin heavy constant delta
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
NRCAM neuronal cell adhesion molecule
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SPINK1 serine peptidase inhibitor, Kazal type 1