BRD-K58288048_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

37 genes differentially expressed following the BRD-K58288048_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ARF4 ADP-ribosylation factor 4
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
CALR calreticulin
CHPT1 choline phosphotransferase 1
COL9A3 collagen, type IX, alpha 3
FADS1 fatty acid desaturase 1
FCGBP Fc fragment of IgG binding protein
FOS FBJ murine osteosarcoma viral oncogene homolog
GDF15 growth differentiation factor 15
GNG11 guanine nucleotide binding protein (G protein), gamma 11
H1F0 H1 histone family, member 0
H1FX H1 histone family, member X
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HSPA1A heat shock 70kDa protein 1A
IER3 immediate early response 3
IGFBP4 insulin-like growth factor binding protein 4
IGFBP6 insulin-like growth factor binding protein 6
INSIG1 insulin induced gene 1
MSL1 male-specific lethal 1 homolog (Drosophila)
MSMO1 methylsterol monooxygenase 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
PLAT plasminogen activator, tissue
PROM1 prominin 1
PRSS3 protease, serine, 3
TFF1 trefoil factor 1
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
WIPI1 WD repeat domain, phosphoinositide interacting 1
XBP1 X-box binding protein 1

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ARL4C ADP-ribosylation factor-like 4C
DEFB1 defensin, beta 1
S100A8 S100 calcium binding protein A8
SPON1 spondin 1, extracellular matrix protein
STK26 serine/threonine protein kinase 26