BRD-K58288048_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

93 genes differentially expressed following the BRD-K58288048_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AHNAK AHNAK nucleoprotein
AIM1 absent in melanoma 1
ANOS1 anosmin 1
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARMCX2 armadillo repeat containing, X-linked 2
BLNK B-cell linker
CALCRL calcitonin receptor-like
CCND2 cyclin D2
CD93 CD93 molecule
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
COLEC12 collectin sub-family member 12
COTL1 coactosin-like F-actin binding protein 1
CRABP1 cellular retinoic acid binding protein 1
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CYBRD1 cytochrome b reductase 1
DDIT4 DNA-damage-inducible transcript 4
DIAPH2 diaphanous-related formin 2
DKK3 dickkopf WNT signaling pathway inhibitor 3
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
EDNRA endothelin receptor type A
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EFNB2 ephrin-B2
EHF ets homologous factor
EMP1 epithelial membrane protein 1
GREM1 gremlin 1, DAN family BMP antagonist
H1F0 H1 histone family, member 0
HEPH hephaestin
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HOXA10 homeobox A10
IGFBP5 insulin-like growth factor binding protein 5
IL10RA interleukin 10 receptor, alpha
INHBA inhibin, beta A
KIAA0226L KIAA0226-like
KLF4 Kruppel-like factor 4 (gut)
LGALS1 lectin, galactoside-binding, soluble, 1
LPAR6 lysophosphatidic acid receptor 6
LTA4H leukotriene A4 hydrolase
LXN latexin
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAP2K6 mitogen-activated protein kinase kinase 6
MB myoglobin
METTL7A methyltransferase like 7A
MFAP5 microfibrillar associated protein 5
MGP matrix Gla protein
MYO10 myosin X
NLGN4X neuroligin 4, X-linked
NPTX2 neuronal pentraxin II
NT5E 5'-nucleotidase, ecto (CD73)
NUPR1 nuclear protein, transcriptional regulator, 1
PADI2 peptidyl arginine deiminase, type II
PDE4B phosphodiesterase 4B, cAMP-specific
PDGFD platelet derived growth factor D
PFKM phosphofructokinase, muscle
PLAU plasminogen activator, urokinase
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PROM1 prominin 1
PRR15L proline rich 15-like
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RGS10 regulator of G-protein signaling 10
RNASE6 ribonuclease, RNase A family, k6
RPL37A ribosomal protein L37a
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SOX9 SRY (sex determining region Y)-box 9
STON1 stonin 1
TMSB15A thymosin beta 15a
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TOR1A torsin family 1, member A (torsin A)
TRIM2 tripartite motif containing 2
TSPAN8 tetraspanin 8
TUBA1A tubulin, alpha 1a
TXNIP thioredoxin interacting protein
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
CCL19 chemokine (C-C motif) ligand 19
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CXCL13 chemokine (C-X-C motif) ligand 13
DHRS2 dehydrogenase/reductase (SDR family) member 2
DKK1 dickkopf WNT signaling pathway inhibitor 1
FAM57A family with sequence similarity 57, member A
GCH1 GTP cyclohydrolase 1
GLUL glutamate-ammonia ligase
JMJD6 jumonji domain containing 6
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MAGEA12 melanoma antigen family A12
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
NR2F6 nuclear receptor subfamily 2, group F, member 6
NUP62 nucleoporin 62kDa
RBP4 retinol binding protein 4, plasma
SSX1 synovial sarcoma, X breakpoint 1