BRD-K58247702_NCGC00183913-01_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

73 genes differentially expressed following the BRD-K58247702_NCGC00183913-01_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide
BAG3 BCL2-associated athanogene 3
BLVRA biliverdin reductase A
CCND3 cyclin D3
CHPT1 choline phosphotransferase 1
CPVL carboxypeptidase, vitellogenic-like
CXCL5 chemokine (C-X-C motif) ligand 5
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
FADS1 fatty acid desaturase 1
FOXO4 forkhead box O4
FYN FYN proto-oncogene, Src family tyrosine kinase
GLRX glutaredoxin (thioltransferase)
GNG12 guanine nucleotide binding protein (G protein), gamma 12
HEBP1 heme binding protein 1
HSPA1A heat shock 70kDa protein 1A
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
LMO2 LIM domain only 2 (rhombotin-like 1)
MAGED1 melanoma antigen family D1
METRN meteorin, glial cell differentiation regulator
MLF1 myeloid leukemia factor 1
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
NPC2 Niemann-Pick disease, type C2
NRIP1 nuclear receptor interacting protein 1
OPN3 opsin 3
PALLD palladin, cytoskeletal associated protein
PGM1 phosphoglucomutase 1
PLAC8 placenta-specific 8
PLS1 plastin 1
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTP4A2 protein tyrosine phosphatase type IVA, member 2
QPCT glutaminyl-peptide cyclotransferase
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RBM47 RNA binding motif protein 47
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
RPL37A ribosomal protein L37a
RPS11 ribosomal protein S11
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SNAP23 synaptosomal-associated protein, 23kDa
STK26 serine/threonine protein kinase 26
STXBP1 syntaxin binding protein 1
TBC1D4 TBC1 domain family, member 4
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGM2 transglutaminase 2
TM4SF1 transmembrane 4 L six family member 1
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TRAM1 translocation associated membrane protein 1
VAT1 vesicle amine transport 1
ZNF185 zinc finger protein 185 (LIM domain)

decreased expression

Symbol Name
ATF5 activating transcription factor 5
AUTS2 autism susceptibility candidate 2
CPA3 carboxypeptidase A3 (mast cell)
CPE carboxypeptidase E
CXCL11 chemokine (C-X-C motif) ligand 11
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
EIF5 eukaryotic translation initiation factor 5
FBXO21 F-box protein 21
FOSL1 FOS-like antigen 1
FST follistatin
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HP haptoglobin
LAMA4 laminin, alpha 4
LOC100505650 uncharacterized LOC100505650
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PPP1R13B protein phosphatase 1, regulatory subunit 13B
RPL10 ribosomal protein L10
SCGB2A1 secretoglobin, family 2A, member 1
SPARCL1 SPARC-like 1 (hevin)
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon