BRD-K58191509_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

65 genes differentially expressed following the BRD-K58191509_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ARG2 arginase 2
ASNS asparagine synthetase (glutamine-hydrolyzing)
ASS1 argininosuccinate synthase 1
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CTH cystathionine gamma-lyase
DDIT4 DNA-damage-inducible transcript 4
FCGBP Fc fragment of IgG binding protein
HCAR3 hydroxycarboxylic acid receptor 3
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
IKZF1 IKAROS family zinc finger 1 (Ikaros)
LPCAT1 lysophosphatidylcholine acyltransferase 1
MAP1B microtubule-associated protein 1B
NAMPT nicotinamide phosphoribosyltransferase
NPTX2 neuronal pentraxin II
PEG10 paternally expressed 10
PNMAL1 paraneoplastic Ma antigen family-like 1
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform
QPRT quinolinate phosphoribosyltransferase
SCUBE2 signal peptide, CUB domain, EGF-like 2
STK10 serine/threonine kinase 10
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TRIM2 tripartite motif containing 2
TSC22D3 TSC22 domain family, member 3
WARS tryptophanyl-tRNA synthetase

decreased expression

Symbol Name
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ANPEP alanyl (membrane) aminopeptidase
ANXA1 annexin A1
CAB39 calcium binding protein 39
CD52 CD52 molecule
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
CRISP3 cysteine-rich secretory protein 3
CTSZ cathepsin Z
DKK1 dickkopf WNT signaling pathway inhibitor 1
DUSP10 dual specificity phosphatase 10
ECM1 extracellular matrix protein 1
FOSL1 FOS-like antigen 1
GLIPR1 GLI pathogenesis-related 1
HBEGF heparin-binding EGF-like growth factor
HOPX HOP homeobox
HOXC6 homeobox C6
KLK10 kallikrein-related peptidase 10
KLK11 kallikrein-related peptidase 11
KRT6B keratin 6B, type II
KYNU kynureninase
LHFP lipoma HMGIC fusion partner
NUP88 nucleoporin 88kDa
PDE4B phosphodiesterase 4B, cAMP-specific
PDLIM5 PDZ and LIM domain 5
RRP8 ribosomal RNA processing 8, methyltransferase, homolog (yeast)
S100A2 S100 calcium binding protein A2
SATB1 SATB homeobox 1
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SPRR3 small proline-rich protein 3
SRC SRC proto-oncogene, non-receptor tyrosine kinase
TBC1D31 TBC1 domain family, member 31
TCF4 transcription factor 4
TM4SF1 transmembrane 4 L six family member 1
TNS3 tensin 3
TPPP3 tubulin polymerization-promoting protein family member 3
TRPS1 trichorhinophalangeal syndrome I
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1