BRD-K57309821_-666_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

76 genes differentially expressed following the BRD-K57309821_-666_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACSL1 acyl-CoA synthetase long-chain family member 1
ADM adrenomedullin
AHR aryl hydrocarbon receptor
AIM1 absent in melanoma 1
ALB albumin
BHLHE40 basic helix-loop-helix family, member e40
C6ORF62 chromosome 6 open reading frame 62
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
COL3A1 collagen, type III, alpha 1
CP ceruloplasmin (ferroxidase)
CSRP1 cysteine and glycine-rich protein 1
CXCL9 chemokine (C-X-C motif) ligand 9
DHRS2 dehydrogenase/reductase (SDR family) member 2
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DPYD dihydropyrimidine dehydrogenase
DSP desmoplakin
F13A1 coagulation factor XIII, A1 polypeptide
HACD2 3-hydroxyacyl-CoA dehydratase 2
HAPLN1 hyaluronan and proteoglycan link protein 1
HK2 hexokinase 2
HOPX HOP homeobox
HSPH1 heat shock 105kDa/110kDa protein 1
IGFBP5 insulin-like growth factor binding protein 5
IL17RB interleukin 17 receptor B
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16
KRT14 keratin 14, type I
KRT17 keratin 17, type I
LPAR6 lysophosphatidic acid receptor 6
MAN1A1 mannosidase, alpha, class 1A, member 1
MT2A metallothionein 2A
MTA1 metastasis associated 1
NRIP1 nuclear receptor interacting protein 1
PCSK1 proprotein convertase subtilisin/kexin type 1
PDE4B phosphodiesterase 4B, cAMP-specific
PDGFC platelet derived growth factor C
PDZD2 PDZ domain containing 2
POSTN periostin, osteoblast specific factor
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PTGER4 prostaglandin E receptor 4 (subtype EP4)
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SDC2 syndecan 2
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SPARCL1 SPARC-like 1 (hevin)
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TFRC transferrin receptor
THBS2 thrombospondin 2
TLR4 toll-like receptor 4
TM4SF1 transmembrane 4 L six family member 1
TOP1 topoisomerase (DNA) I
TRPS1 trichorhinophalangeal syndrome I

decreased expression

Symbol Name
AUTS2 autism susceptibility candidate 2
BIK BCL2-interacting killer (apoptosis-inducing)
BTG1 B-cell translocation gene 1, anti-proliferative
CD9 CD9 molecule
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLC Charcot-Leyden crystal galectin
CTSG cathepsin G
CYTL1 cytokine-like 1
FCGBP Fc fragment of IgG binding protein
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
FOXF1 forkhead box F1
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
ITM2C integral membrane protein 2C
MBP myelin basic protein
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
OLFM4 olfactomedin 4
PENK proenkephalin
PIH1D1 PIH1 domain containing 1
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
RCAN1 regulator of calcineurin 1
STAB1 stabilin 1
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TXNIP thioredoxin interacting protein
UGCG UDP-glucose ceramide glucosyltransferase
ZBTB18 zinc finger and BTB domain containing 18