BRD-K57309821_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

33 genes differentially expressed following the BRD-K57309821_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADAMDEC1 ADAM-like, decysin 1
ARG2 arginase 2
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
CD40 CD40 molecule, TNF receptor superfamily member 5
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
EPAS1 endothelial PAS domain protein 1
FGFR2 fibroblast growth factor receptor 2
GREM1 gremlin 1, DAN family BMP antagonist
JCHAIN joining chain of multimeric IgA and IgM
MAPT microtubule-associated protein tau
MEST mesoderm specific transcript
MME membrane metallo-endopeptidase
MMP12 matrix metallopeptidase 12
NT5E 5'-nucleotidase, ecto (CD73)
RPS4Y1 ribosomal protein S4, Y-linked 1
RTN1 reticulon 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)

decreased expression

Symbol Name
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
BST2 bone marrow stromal cell antigen 2
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CNPY3 canopy FGF signaling regulator 3
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
IGF1R insulin-like growth factor 1 receptor
IKZF1 IKAROS family zinc finger 1 (Ikaros)
NR1D2 nuclear receptor subfamily 1, group D, member 2
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
RPL37A ribosomal protein L37a
XAF1 XIAP associated factor 1
ZDHHC6 zinc finger, DHHC-type containing 6