BRD-K57304726_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

29 genes differentially expressed following the BRD-K57304726_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
C2CD2 C2 calcium-dependent domain containing 2
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DUSP10 dual specificity phosphatase 10
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
KDM5D lysine (K)-specific demethylase 5D
KRT4 keratin 4, type II
PLK2 polo-like kinase 2
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RNF167 ring finger protein 167
RPS4Y1 ribosomal protein S4, Y-linked 1

decreased expression

Symbol Name
ALB albumin
COL1A1 collagen, type I, alpha 1
CPE carboxypeptidase E
HOPX HOP homeobox
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
PON3 paraoxonase 3
POSTN periostin, osteoblast specific factor
PVALB parvalbumin
SEPP1 selenoprotein P, plasma, 1
SMAD1 SMAD family member 1
THY1 Thy-1 cell surface antigen