BRD-K57282030_JW-7-24-1_MCF7_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

94 genes differentially expressed following the BRD-K57282030_JW-7-24-1_MCF7_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AGR2 anterior gradient 2
BEX1 brain expressed, X-linked 1
BHLHE41 basic helix-loop-helix family, member e41
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
C1QA complement component 1, q subcomponent, A chain
C1QB complement component 1, q subcomponent, B chain
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CCNG2 cyclin G2
CD163 CD163 molecule
CRISP3 cysteine-rich secretory protein 3
CTDSP2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
CTGF connective tissue growth factor
EIF4B eukaryotic translation initiation factor 4B
ERBB2 erb-b2 receptor tyrosine kinase 2
FOS FBJ murine osteosarcoma viral oncogene homolog
GLTSCR2 glioma tumor suppressor candidate region gene 2
GLUL glutamate-ammonia ligase
GPNMB glycoprotein (transmembrane) nmb
GRN granulin
HBP1 HMG-box transcription factor 1
HES1 hes family bHLH transcription factor 1
HIST1H2AC histone cluster 1, H2ac
IGF1R insulin-like growth factor 1 receptor
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
LETMD1 LETM1 domain containing 1
MARCKS myristoylated alanine-rich protein kinase C substrate
MT1F metallothionein 1F
MT1H metallothionein 1H
MT1X metallothionein 1X
MZF1 myeloid zinc finger 1
NTS neurotensin
PCGF2 polycomb group ring finger 2
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PNRC1 proline-rich nuclear receptor coactivator 1
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
POLR1D polymerase (RNA) I polypeptide D, 16kDa
QPCT glutaminyl-peptide cyclotransferase
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RGS13 regulator of G-protein signaling 13
RPS27L ribosomal protein S27-like
SDCBP syndecan binding protein (syntenin)
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SORBS3 sorbin and SH3 domain containing 3
SYF2 SYF2 pre-mRNA-splicing factor
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TNS3 tensin 3
TSPAN1 tetraspanin 1
TXNIP thioredoxin interacting protein
VAT1 vesicle amine transport 1

decreased expression

Symbol Name
ACOT7 acyl-CoA thioesterase 7
ADD3 adducin 3 (gamma)
ANPEP alanyl (membrane) aminopeptidase
ATAD2 ATPase family, AAA domain containing 2
BTG3 BTG family, member 3
C20ORF24 chromosome 20 open reading frame 24
CCND3 cyclin D3
CDC25A cell division cycle 25A
CYCS cytochrome c, somatic
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
ENDOD1 endonuclease domain containing 1
EREG epiregulin
FEN1 flap structure-specific endonuclease 1
FYN FYN proto-oncogene, Src family tyrosine kinase
GGCT gamma-glutamylcyclotransferase
GINS1 GINS complex subunit 1 (Psf1 homolog)
GINS2 GINS complex subunit 2 (Psf2 homolog)
GLIPR1 GLI pathogenesis-related 1
H2AFX H2A histone family, member X
HBEGF heparin-binding EGF-like growth factor
IGKC immunoglobulin kappa constant
ISG15 ISG15 ubiquitin-like modifier
ISOC1 isochorismatase domain containing 1
MCM10 minichromosome maintenance complex component 10
MELK maternal embryonic leucine zipper kinase
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2
NPR3 natriuretic peptide receptor 3
NQO1 NAD(P)H dehydrogenase, quinone 1
NRGN neurogranin (protein kinase C substrate, RC3)
PCP4 Purkinje cell protein 4
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
POSTN periostin, osteoblast specific factor
PPIF peptidylprolyl isomerase F
PRPF4 pre-mRNA processing factor 4
RPN2 ribophorin II
S100A7 S100 calcium binding protein A7
SLBP stem-loop binding protein
SMCO4 single-pass membrane protein with coiled-coil domains 4
TDO2 tryptophan 2,3-dioxygenase
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TSPYL5 TSPY-like 5
TUBG1 tubulin, gamma 1
ZWINT ZW10 interacting kinetochore protein