BRD-K57282030_JW-7-24-1_BT20_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

80 genes differentially expressed following the BRD-K57282030_JW-7-24-1_BT20_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AEBP1 AE binding protein 1
C7 complement component 7
CCL5 chemokine (C-C motif) ligand 5
CCND2 cyclin D2
CD24 CD24 molecule
CD9 CD9 molecule
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
COCH cochlin
COL5A2 collagen, type V, alpha 2
CPB1 carboxypeptidase B1 (tissue)
DCN decorin
DHRS2 dehydrogenase/reductase (SDR family) member 2
DPYSL3 dihydropyrimidinase-like 3
EDNRA endothelin receptor type A
FGG fibrinogen gamma chain
FILIP1L filamin A interacting protein 1-like
FZD7 frizzled class receptor 7
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
IGHMBP2 immunoglobulin mu binding protein 2
IL7R interleukin 7 receptor
ITM2A integral membrane protein 2A
KIAA0753 KIAA0753
KRT18 keratin 18, type I
LPAR6 lysophosphatidic acid receptor 6
MAN1A1 mannosidase, alpha, class 1A, member 1
MEIS2 Meis homeobox 2
MN1 meningioma (disrupted in balanced translocation) 1
NID2 nidogen 2 (osteonidogen)
NOTCH2 notch 2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
PDE10A phosphodiesterase 10A
PEG10 paternally expressed 10
PID1 phosphotyrosine interaction domain containing 1
PPAP2A phosphatidic acid phosphatase type 2A
RGS5 regulator of G-protein signaling 5
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
SDC4 syndecan 4
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SFRP1 secreted frizzled-related protein 1
STC1 stanniocalcin 1
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae)
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
WIPF1 WAS/WASL interacting protein family, member 1

decreased expression

Symbol Name
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa
CD320 CD320 molecule
CD59 CD59 molecule, complement regulatory protein
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR4 chemokine (C-X-C motif) receptor 4
F2RL1 coagulation factor II (thrombin) receptor-like 1
FABP4 fatty acid binding protein 4, adipocyte
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAR2 fatty acyl CoA reductase 2
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
HBEGF heparin-binding EGF-like growth factor
IFI6 interferon, alpha-inducible protein 6
ITGA6 integrin, alpha 6
KIAA0125 KIAA0125
KRT20 keratin 20, type I
MAB21L2 mab-21-like 2 (C. elegans)
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
PI3 peptidase inhibitor 3, skin-derived
PLAC8 placenta-specific 8
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PRDX2 peroxiredoxin 2
PROM1 prominin 1
PSAT1 phosphoserine aminotransferase 1
RBP1 retinol binding protein 1, cellular
RGS4 regulator of G-protein signaling 4
RNASET2 ribonuclease T2
RPS26 ribosomal protein S26
S100B S100 calcium binding protein B
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SOX9 SRY (sex determining region Y)-box 9
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
SRSF6 serine/arginine-rich splicing factor 6
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TUBB2A tubulin, beta 2A class IIa