BRD-K57282030_JW-7-24-1_A549_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

86 genes differentially expressed following the BRD-K57282030_JW-7-24-1_A549_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADIPOR2 adiponectin receptor 2
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
ALDOC aldolase C, fructose-bisphosphate
BEX1 brain expressed, X-linked 1
CAV2 caveolin 2
CCNG1 cyclin G1
DNTT DNA nucleotidylexotransferase
DUSP4 dual specificity phosphatase 4
EMP1 epithelial membrane protein 1
FCMR Fc fragment of IgM receptor
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FLRT2 fibronectin leucine rich transmembrane protein 2
H3F3B H3 histone, family 3B (H3.3B)
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IGF1R insulin-like growth factor 1 receptor
IRS2 insulin receptor substrate 2
JADE2 jade family PHD finger 2
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
LDOC1 leucine zipper, down-regulated in cancer 1
LOC100272216 uncharacterized LOC100272216
LPAR2 lysophosphatidic acid receptor 2
LXN latexin
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MANSC1 MANSC domain containing 1
MYO6 myosin VI
POU2AF1 POU class 2 associating factor 1
PXMP2 peroxisomal membrane protein 2, 22kDa
RAB13 RAB13, member RAS oncogene family
RBM34 RNA binding motif protein 34
RPL31 ribosomal protein L31
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SFTPA2 surfactant protein A2
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SST somatostatin
STAP2 signal transducing adaptor family member 2
TCF4 transcription factor 4
TIMP3 TIMP metallopeptidase inhibitor 3
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TLR4 toll-like receptor 4
TRAPPC6A trafficking protein particle complex 6A
UBE2J1 ubiquitin-conjugating enzyme E2, J1
VAT1 vesicle amine transport 1
XIST X inactive specific transcript (non-protein coding)
ZIC1 Zic family member 1

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
ABHD6 abhydrolase domain containing 6
ACTA2 actin, alpha 2, smooth muscle, aorta
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
AQP3 aquaporin 3 (Gill blood group)
BOP1 block of proliferation 1
CDC20 cell division cycle 20
CDC42 cell division cycle 42
COL10A1 collagen, type X, alpha 1
COL1A1 collagen, type I, alpha 1
CXCL14 chemokine (C-X-C motif) ligand 14
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
DHRS2 dehydrogenase/reductase (SDR family) member 2
EIF5A eukaryotic translation initiation factor 5A
GAL galanin/GMAP prepropeptide
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
IGFBP5 insulin-like growth factor binding protein 5
KIF20A kinesin family member 20A
KYNU kynureninase
LAPTM4B lysosomal protein transmembrane 4 beta
LYPLA1 lysophospholipase I
MARS methionyl-tRNA synthetase
MYLK myosin light chain kinase
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PFN2 profilin 2
PHGDH phosphoglycerate dehydrogenase
PLAC8 placenta-specific 8
PSAT1 phosphoserine aminotransferase 1
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RGS2 regulator of G-protein signaling 2
S100P S100 calcium binding protein P
SFRP4 secreted frizzled-related protein 4
SPARCL1 SPARC-like 1 (hevin)
STIP1 stress-induced phosphoprotein 1
TNC tenascin C
TXNDC9 thioredoxin domain containing 9
VCAM1 vascular cell adhesion molecule 1
YKT6 YKT6 v-SNARE homolog (S. cerevisiae)