BRD-K57179821_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

20 genes differentially expressed following the BRD-K57179821_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
BASP1 brain abundant, membrane attached signal protein 1
CD59 CD59 molecule, complement regulatory protein
EGFR epidermal growth factor receptor
IGKV1-5 immunoglobulin kappa variable 1-5
IQCG IQ motif containing G
LSR lipolysis stimulated lipoprotein receptor
TIMP4 TIMP metallopeptidase inhibitor 4
TNC tenascin C

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CD93 CD93 molecule
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CDKN2A cyclin-dependent kinase inhibitor 2A
CES1 carboxylesterase 1
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
FGG fibrinogen gamma chain
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
MGP matrix Gla protein
RFX5 regulatory factor X, 5 (influences HLA class II expression)
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
THY1 Thy-1 cell surface antigen