BRD-K57179821_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

99 genes differentially expressed following the BRD-K57179821_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ADARB1 adenosine deaminase, RNA-specific, B1
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
AMPD3 adenosine monophosphate deaminase 3
ARID4B AT rich interactive domain 4B (RBP1-like)
AUTS2 autism susceptibility candidate 2
BASP1 brain abundant, membrane attached signal protein 1
CLCA2 chloride channel accessory 2
CLU clusterin
CST3 cystatin C
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DSP desmoplakin
DST dystonin
FAIM Fas apoptotic inhibitory molecule
FOLR1 folate receptor 1 (adult)
GAL galanin/GMAP prepropeptide
GATA3 GATA binding protein 3
GCLC glutamate-cysteine ligase, catalytic subunit
GCLM glutamate-cysteine ligase, modifier subunit
GRIA2 glutamate receptor, ionotropic, AMPA 2
GSTA4 glutathione S-transferase alpha 4
IRF8 interferon regulatory factor 8
KRT6A keratin 6A, type II
KRT7 keratin 7, type II
LY86 lymphocyte antigen 86
MAP3K8 mitogen-activated protein kinase kinase kinase 8
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MPP1 membrane protein, palmitoylated 1, 55kDa
MPPED2 metallophosphoesterase domain containing 2
NID2 nidogen 2 (osteonidogen)
NT5DC2 5'-nucleotidase domain containing 2
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PLAGL1 pleiomorphic adenoma gene-like 1
PLD3 phospholipase D family, member 3
PRF1 perforin 1 (pore forming protein)
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
RAB31 RAB31, member RAS oncogene family
RBP1 retinol binding protein 1, cellular
RCAN2 regulator of calcineurin 2
REEP1 receptor accessory protein 1
REG1A regenerating islet-derived 1 alpha
RNF167 ring finger protein 167
SEPP1 selenoprotein P, plasma, 1
SEPT6 septin 6
SFTPA2 surfactant protein A2
SFTPB surfactant protein B
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SYBU syntabulin (syntaxin-interacting)
TGFBI transforming growth factor, beta-induced, 68kDa
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TPD52L1 tumor protein D52-like 1
TRD T cell receptor delta locus
TSC22D1 TSC22 domain family, member 1
ZNF652 zinc finger protein 652

decreased expression

Symbol Name
ACP1 acid phosphatase 1, soluble
ACSL3 acyl-CoA synthetase long-chain family member 3
ALB albumin
ANXA1 annexin A1
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
ATF5 activating transcription factor 5
CAV1 caveolin 1, caveolae protein, 22kDa
CD200 CD200 molecule
CD52 CD52 molecule
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CLEC11A C-type lectin domain family 11, member A
CYCS cytochrome c, somatic
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
DENND1B DENN/MADD domain containing 1B
DOK5 docking protein 5
DPYSL2 dihydropyrimidinase-like 2
ECM1 extracellular matrix protein 1
EIF5 eukaryotic translation initiation factor 5
FABP4 fatty acid binding protein 4, adipocyte
FN1 fibronectin 1
HAT1 histone acetyltransferase 1
HIST1H4C histone cluster 1, H4c
IGFBP3 insulin-like growth factor binding protein 3
ISG20 interferon stimulated exonuclease gene 20kDa
KRT23 keratin 23, type I
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MOK MOK protein kinase
MRPS16 mitochondrial ribosomal protein S16
MYH10 myosin, heavy chain 10, non-muscle
PEG10 paternally expressed 10
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRRC2C proline-rich coiled-coil 2C
RFTN1 raftlin, lipid raft linker 1
RGCC regulator of cell cycle
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
SFRP1 secreted frizzled-related protein 1
SGCE sarcoglycan, epsilon
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
UBE2E3 ubiquitin-conjugating enzyme E2E 3
VCL vinculin