BRD-K57080016_-666_SW620_6.0_h_80.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

82 genes differentially expressed following the BRD-K57080016_-666_SW620_6.0_h_80.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACSL1 acyl-CoA synthetase long-chain family member 1
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C2 aldo-keto reductase family 1, member C2
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CD81 CD81 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CLIC5 chloride intracellular channel 5
CYFIP2 cytoplasmic FMR1 interacting protein 2
DDIT4 DNA-damage-inducible transcript 4
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FBXO11 F-box protein 11
GJA1 gap junction protein, alpha 1, 43kDa
GREM1 gremlin 1, DAN family BMP antagonist
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IGHD immunoglobulin heavy constant delta
IGKC immunoglobulin kappa constant
IGKV4-1 immunoglobulin kappa variable 4-1
IGL immunoglobulin lambda locus
IL1R1 interleukin 1 receptor, type I
KDM5D lysine (K)-specific demethylase 5D
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PHGDH phosphoglycerate dehydrogenase
POU2AF1 POU class 2 associating factor 1
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
S100A7 S100 calcium binding protein A7
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SEPP1 selenoprotein P, plasma, 1
SFTPA2 surfactant protein A2
SFTPD surfactant protein D
SLC39A6 solute carrier family 39 (zinc transporter), member 6
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SPP1 secreted phosphoprotein 1
TMEM176B transmembrane protein 176B
TMEM47 transmembrane protein 47
TPBG trophoblast glycoprotein

decreased expression

Symbol Name
CARD10 caspase recruitment domain family, member 10
CHIC2 cysteine-rich hydrophobic domain 2
CTGF connective tissue growth factor
CXCL8 chemokine (C-X-C motif) ligand 8
DKK1 dickkopf WNT signaling pathway inhibitor 1
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha)
DUSP4 dual specificity phosphatase 4
DUSP6 dual specificity phosphatase 6
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
ENC1 ectodermal-neural cortex 1 (with BTB domain)
ETV5 ets variant 5
FOSL1 FOS-like antigen 1
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GNG11 guanine nucleotide binding protein (G protein), gamma 11
HES1 hes family bHLH transcription factor 1
HMGA2 high mobility group AT-hook 2
HSPA1A heat shock 70kDa protein 1A
IER3 immediate early response 3
ISG20 interferon stimulated exonuclease gene 20kDa
ITGA6 integrin, alpha 6
LGALS1 lectin, galactoside-binding, soluble, 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAOB monoamine oxidase B
MARCKSL1 MARCKS-like 1
MDK midkine (neurite growth-promoting factor 2)
NCALD neurocalcin delta
NID1 nidogen 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PLAT plasminogen activator, tissue
RNPS1 RNA binding protein S1, serine-rich domain
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SOX4 SRY (sex determining region Y)-box 4
SOX9 SRY (sex determining region Y)-box 9
TFF1 trefoil factor 1
TFF3 trefoil factor 3 (intestinal)
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TM4SF1 transmembrane 4 L six family member 1
TNFRSF21 tumor necrosis factor receptor superfamily, member 21