BRD-K57037351_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

91 genes differentially expressed following the BRD-K57037351_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKAP12 A kinase (PRKA) anchor protein 12
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATHL1 ATH1, acid trehalase-like 1 (yeast)
BACE2 beta-site APP-cleaving enzyme 2
BIN1 bridging integrator 1
CAPG capping protein (actin filament), gelsolin-like
CBS cystathionine-beta-synthase
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase
CELF2 CUGBP, Elav-like family member 2
CORO1A coronin, actin binding protein, 1A
DACH1 dachshund family transcription factor 1
DDIT4 DNA-damage-inducible transcript 4
DUSP4 dual specificity phosphatase 4
FAR2 fatty acyl CoA reductase 2
GATA6 GATA binding protein 6
HMOX1 heme oxygenase 1
IFITM1 interferon induced transmembrane protein 1
LCN2 lipocalin 2
LIPG lipase, endothelial
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1H metallothionein 1H
MT1X metallothionein 1X
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
NEBL nebulette
NEFH neurofilament, heavy polypeptide
OLFM4 olfactomedin 4
PGLS 6-phosphogluconolactonase
PHGDH phosphoglycerate dehydrogenase
PHYH phytanoyl-CoA 2-hydroxylase
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PLBD1 phospholipase B domain containing 1
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RBP1 retinol binding protein 1, cellular
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13
SORD sorbitol dehydrogenase
SOX9 SRY (sex determining region Y)-box 9
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
TBX3 T-box 3
TGFBI transforming growth factor, beta-induced, 68kDa
TSKU tsukushi, small leucine rich proteoglycan
VIM vimentin
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
ADCY1 adenylate cyclase 1 (brain)
ALOX5 arachidonate 5-lipoxygenase
AQP3 aquaporin 3 (Gill blood group)
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1
ARMC1 armadillo repeat containing 1
ASPH aspartate beta-hydroxylase
CA12 carbonic anhydrase XII
CA2 carbonic anhydrase II
CCNA2 cyclin A2
CDK1 cyclin-dependent kinase 1
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
COL4A5 collagen, type IV, alpha 5
CRISP3 cysteine-rich secretory protein 3
DHRS2 dehydrogenase/reductase (SDR family) member 2
DLG5 discs, large homolog 5 (Drosophila)
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9
ESR1 estrogen receptor 1
FOLR1 folate receptor 1 (adult)
FXYD2 FXYD domain containing ion transport regulator 2
GRB14 growth factor receptor-bound protein 14
GTF2A2 general transcription factor IIA, 2, 12kDa
HIST1H1C histone cluster 1, H1c
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
ISOC1 isochorismatase domain containing 1
KIAA0101 KIAA0101
KIF14 kinesin family member 14
LAMP2 lysosomal-associated membrane protein 2
LTF lactotransferrin
LYPLA1 lysophospholipase I
MUC1 mucin 1, cell surface associated
NPY1R neuropeptide Y receptor Y1
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase
PPIF peptidylprolyl isomerase F
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
RRM2 ribonucleotide reductase M2
SAR1A secretion associated, Ras related GTPase 1A
SAR1B secretion associated, Ras related GTPase 1B
SELT selenoprotein T
SGK1 serum/glucocorticoid regulated kinase 1
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
TRAM1 translocation associated membrane protein 1
TSPYL5 TSPY-like 5
UBE2A ubiquitin-conjugating enzyme E2A
ZWINT ZW10 interacting kinetochore protein