BRD-K56751279_Y-39983_HS578T_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

57 genes differentially expressed following the BRD-K56751279_Y-39983_HS578T_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
CA1 carbonic anhydrase I
CA12 carbonic anhydrase XII
CADM1 cell adhesion molecule 1
CD44 CD44 molecule (Indian blood group)
DDIT4 DNA-damage-inducible transcript 4
MAB21L2 mab-21-like 2 (C. elegans)
PCOLCE procollagen C-endopeptidase enhancer
POSTN periostin, osteoblast specific factor
RPL39L ribosomal protein L39-like
SAP30 Sin3A-associated protein, 30kDa
SFN stratifin
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
TUSC3 tumor suppressor candidate 3

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRG6 adhesion G protein-coupled receptor G6
ADRB2 adrenoceptor beta 2, surface
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
AMIGO2 adhesion molecule with Ig-like domain 2
ANXA3 annexin A3
ATF3 activating transcription factor 3
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
CCND2 cyclin D2
CD200 CD200 molecule
CDH3 cadherin 3, type 1, P-cadherin (placental)
CPE carboxypeptidase E
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
CTGF connective tissue growth factor
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL9 chemokine (C-X-C motif) ligand 9
CYR61 cysteine-rich, angiogenic inducer, 61
EDN1 endothelin 1
EGR2 early growth response 2
EIF5 eukaryotic translation initiation factor 5
F11R F11 receptor
GADD45A growth arrest and DNA-damage-inducible, alpha
GDF15 growth differentiation factor 15
HIST1H1C histone cluster 1, H1c
HIST1H4C histone cluster 1, H4c
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
IFI16 interferon, gamma-inducible protein 16
LEF1 lymphoid enhancer-binding factor 1
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LYZ lysozyme
PEG3 paternally expressed 3
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
RGCC regulator of cell cycle
RTN1 reticulon 1
S100P S100 calcium binding protein P
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TPPP3 tubulin polymerization-promoting protein family member 3
WWP1 WW domain containing E3 ubiquitin protein ligase 1