BRD-K56751279_Y-39983_HS578T_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

50 genes differentially expressed following the BRD-K56751279_Y-39983_HS578T_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CA12 carbonic anhydrase XII
CCNA1 cyclin A1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FCGBP Fc fragment of IgG binding protein
GPX3 glutathione peroxidase 3
IGKC immunoglobulin kappa constant
IGL immunoglobulin lambda locus
IGLV2-23 immunoglobulin lambda variable 2-23
JCHAIN joining chain of multimeric IgA and IgM
KDM5D lysine (K)-specific demethylase 5D
LYN LYN proto-oncogene, Src family tyrosine kinase
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
NES nestin
PODXL podocalyxin-like
PTN pleiotrophin
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SFTPB surfactant protein B
SPATS2L spermatogenesis associated, serine-rich 2-like
TUBB6 tubulin, beta 6 class V

decreased expression

Symbol Name
ADIRF adipogenesis regulatory factor
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
ANXA3 annexin A3
ATF3 activating transcription factor 3
BIRC3 baculoviral IAP repeat containing 3
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
COL10A1 collagen, type X, alpha 1
COL11A1 collagen, type XI, alpha 1
COMP cartilage oligomeric matrix protein
CPE carboxypeptidase E
CTGF connective tissue growth factor
CYR61 cysteine-rich, angiogenic inducer, 61
EDN1 endothelin 1
HBB hemoglobin, beta
HBD hemoglobin, delta
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IL7R interleukin 7 receptor
MANSC1 MANSC domain containing 1
MME membrane metallo-endopeptidase
NEFH neurofilament, heavy polypeptide
NT5E 5'-nucleotidase, ecto (CD73)
PCP4 Purkinje cell protein 4
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PRPF4 pre-mRNA processing factor 4
S100P S100 calcium binding protein P
SC5D sterol-C5-desaturase
SERINC5 serine incorporator 5
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
THBS1 thrombospondin 1