BRD-K56653679_-666_PC3_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

84 genes differentially expressed following the BRD-K56653679_-666_PC3_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
AQP1 aquaporin 1 (Colton blood group)
ATF3 activating transcription factor 3
BAMBI BMP and activin membrane-bound inhibitor
CD163 CD163 molecule
CDC25A cell division cycle 25A
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CRIP2 cysteine-rich protein 2
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DDIT4 DNA-damage-inducible transcript 4
DEPTOR DEP domain containing MTOR-interacting protein
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DUSP1 dual specificity phosphatase 1
EDNRB endothelin receptor type B
FOS FBJ murine osteosarcoma viral oncogene homolog
GABARAPL1 GABA(A) receptor-associated protein like 1
GAGE3 G antigen 3
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIST1H1C histone cluster 1, H1c
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HMOX1 heme oxygenase 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPB1 heat shock 27kDa protein 1
HSPH1 heat shock 105kDa/110kDa protein 1
IER5 immediate early response 5
IFI30 interferon, gamma-inducible protein 30
IGHM immunoglobulin heavy constant mu
IGKV4-1 immunoglobulin kappa variable 4-1
KLF4 Kruppel-like factor 4 (gut)
LMO4 LIM domain only 4
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
METTL7A methyltransferase like 7A
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
PCDH9 protocadherin 9
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PLBD1 phospholipase B domain containing 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PPP1R3C protein phosphatase 1, regulatory subunit 3C
S100A10 S100 calcium binding protein A10
SDC2 syndecan 2
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
TUSC3 tumor suppressor candidate 3
TWIST1 twist family bHLH transcription factor 1
XBP1 X-box binding protein 1
ZNF331 zinc finger protein 331

decreased expression

Symbol Name
ADCY9 adenylate cyclase 9
AIM1 absent in melanoma 1
AREG amphiregulin
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
CANT1 calcium activated nucleotidase 1
CAV1 caveolin 1, caveolae protein, 22kDa
CCL20 chemokine (C-C motif) ligand 20
CCNA2 cyclin A2
CD44 CD44 molecule (Indian blood group)
CPNE3 copine III
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
DUSP4 dual specificity phosphatase 4
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7
GPRC5A G protein-coupled receptor, class C, group 5, member A
IER3 immediate early response 3
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KLHL9 kelch-like family member 9
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MAGED1 melanoma antigen family D1
MAP1B microtubule-associated protein 1B
MBP myelin basic protein
MYC v-myc avian myelocytomatosis viral oncogene homolog
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NRIP1 nuclear receptor interacting protein 1
NRN1 neuritin 1
OPHN1 oligophrenin 1
RAB38 RAB38, member RAS oncogene family
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SRPX sushi-repeat containing protein, X-linked
STOM stomatin
STXBP2 syntaxin binding protein 2
SYNJ2 synaptojanin 2
TMEM45A transmembrane protein 45A
TNFAIP8 tumor necrosis factor, alpha-induced protein 8
TXLNA taxilin alpha