BRD-K56515112_Medrysone_VCAP_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

39 genes differentially expressed following the BRD-K56515112_Medrysone_VCAP_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABAT 4-aminobutyrate aminotransferase
ARMCX3 armadillo repeat containing, X-linked 3
BEX4 brain expressed, X-linked 4
C3ORF14 chromosome 3 open reading frame 14
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CFB complement factor B
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DLK1 delta-like 1 homolog (Drosophila)
FGB fibrinogen beta chain
FKBP1B FK506 binding protein 1B, 12.6 kDa
FOXO3 forkhead box O3
GLRX glutaredoxin (thioltransferase)
KIAA1324 KIAA1324
LGALS1 lectin, galactoside-binding, soluble, 1
LGMN legumain
MSMB microseminoprotein, beta-
MYBPC1 myosin binding protein C, slow type
NISCH nischarin
PTN pleiotrophin
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
THBS1 thrombospondin 1
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
UGDH UDP-glucose 6-dehydrogenase
ZBTB16 zinc finger and BTB domain containing 16
ZBTB18 zinc finger and BTB domain containing 18

decreased expression

Symbol Name
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
CA12 carbonic anhydrase XII
CDC5L cell division cycle 5-like
HOPX HOP homeobox
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IGFBP3 insulin-like growth factor binding protein 3
MYC v-myc avian myelocytomatosis viral oncogene homolog
PLS3 plastin 3
PNP purine nucleoside phosphorylase
SPRR1B small proline-rich protein 1B