BRD-K56515112_6alpha-methyl-11beta-hydroxyprogesterone_VCAP_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

44 genes differentially expressed following the BRD-K56515112_6alpha-methyl-11beta-hydroxyprogesterone_VCAP_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CA1 carbonic anhydrase I
CPE carboxypeptidase E
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
GLRX glutaredoxin (thioltransferase)
GPER1 G protein-coupled estrogen receptor 1
HBD hemoglobin, delta
HOMER2 homer scaffolding protein 2
IGLL1 immunoglobulin lambda-like polypeptide 1
INSIG1 insulin induced gene 1
KLK11 kallikrein-related peptidase 11
MSMB microseminoprotein, beta-
MSMO1 methylsterol monooxygenase 1
NSDHL NAD(P) dependent steroid dehydrogenase-like
OSBPL10 oxysterol binding protein-like 10
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PHLDA2 pleckstrin homology-like domain, family A, member 2
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
TPM1 tropomyosin 1 (alpha)

decreased expression

Symbol Name
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
BCHE butyrylcholinesterase
BRCA1 breast cancer 1, early onset
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family)
CCNA2 cyclin A2
CCNB2 cyclin B2
CDK1 cyclin-dependent kinase 1
CENPA centromere protein A
CENPE centromere protein E, 312kDa
CENPF centromere protein F, 350/400kDa
CEP55 centrosomal protein 55kDa
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
HIST1H4C histone cluster 1, H4c
HMMR hyaluronan-mediated motility receptor (RHAMM)
KIF20A kinesin family member 20A
KIF2C kinesin family member 2C
KRT7 keratin 7, type II
MELK maternal embryonic leucine zipper kinase
MLF1 myeloid leukemia factor 1
OXCT1 3-oxoacid CoA transferase 1
PBK PDZ binding kinase
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PLK2 polo-like kinase 2
UBE2C ubiquitin-conjugating enzyme E2C