BRD-K56429665_Calcipotriol_A549_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

90 genes differentially expressed following the BRD-K56429665_Calcipotriol_A549_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADAM12 ADAM metallopeptidase domain 12
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
AQP9 aquaporin 9
ARG2 arginase 2
ASNS asparagine synthetase (glutamine-hydrolyzing)
ASS1 argininosuccinate synthase 1
ATF3 activating transcription factor 3
BEX1 brain expressed, X-linked 1
CCL4 chemokine (C-C motif) ligand 4
CD40 CD40 molecule, TNF receptor superfamily member 5
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CLDN3 claudin 3
DDIT4 DNA-damage-inducible transcript 4
DSE dermatan sulfate epimerase
EMX2 empty spiracles homeobox 2
EXPH5 exophilin 5
FGFR2 fibroblast growth factor receptor 2
FTH1 ferritin, heavy polypeptide 1
HBB hemoglobin, beta
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
MAP7 microtubule-associated protein 7
MOCOS molybdenum cofactor sulfurase
MYRF myelin regulatory factor
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PDE4DIP phosphodiesterase 4D interacting protein
PHGDH phosphoglycerate dehydrogenase
PIR pirin (iron-binding nuclear protein)
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PSAT1 phosphoserine aminotransferase 1
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RHOBTB3 Rho-related BTB domain containing 3
RTN1 reticulon 1
SCG5 secretogranin V
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial)
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
STC2 stanniocalcin 2
SYK spleen tyrosine kinase
SYT1 synaptotagmin I
TRIB3 tribbles pseudokinase 3
TRIM2 tripartite motif containing 2
TSC22D3 TSC22 domain family, member 3
WARS tryptophanyl-tRNA synthetase
WNT5A wingless-type MMTV integration site family, member 5A

decreased expression

Symbol Name
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
AURKB aurora kinase B
CBR3 carbonyl reductase 3
CCL19 chemokine (C-C motif) ligand 19
CCNF cyclin F
CD24 CD24 molecule
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CLTB clathrin, light chain B
CTGF connective tissue growth factor
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FGFR4 fibroblast growth factor receptor 4
FHL1 four and a half LIM domains 1
FLRT3 fibronectin leucine rich transmembrane protein 3
FRZB frizzled-related protein
GPX3 glutathione peroxidase 3
HES1 hes family bHLH transcription factor 1
HEXIM1 hexamethylene bis-acetamide inducible 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMGN1 high mobility group nucleosome binding domain 1
HN1 hematological and neurological expressed 1
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
INSIG1 insulin induced gene 1
KRT17 keratin 17, type I
KRT4 keratin 4, type II
KRT5 keratin 5, type II
KRT6A keratin 6A, type II
KRT6B keratin 6B, type II
LUM lumican
MCOLN1 mucolipin 1
MFSD10 major facilitator superfamily domain containing 10
MGP matrix Gla protein
NFIB nuclear factor I/B
NR2F2 nuclear receptor subfamily 2, group F, member 2
NUSAP1 nucleolar and spindle associated protein 1
PGAM1 phosphoglycerate mutase 1 (brain)
PI3 peptidase inhibitor 3, skin-derived
PKM pyruvate kinase, muscle
S100A7 S100 calcium binding protein A7
SPRR1A small proline-rich protein 1A
SPRR1B small proline-rich protein 1B
SRC SRC proto-oncogene, non-receptor tyrosine kinase
TACC3 transforming, acidic coiled-coil containing protein 3
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TIMP3 TIMP metallopeptidase inhibitor 3