BRD-K56277358_MGCD-265_A549_24_h_10_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

25 genes differentially expressed following the BRD-K56277358_MGCD-265_A549_24_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALDOC aldolase C, fructose-bisphosphate
APOB apolipoprotein B
AREG amphiregulin
C8ORF4 chromosome 8 open reading frame 4
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
DHCR7 7-dehydrocholesterol reductase
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FOS FBJ murine osteosarcoma viral oncogene homolog
INSIG1 insulin induced gene 1
ITM2A integral membrane protein 2A
LDLR low density lipoprotein receptor
MAPT microtubule-associated protein tau
MSMO1 methylsterol monooxygenase 1
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC22A18 solute carrier family 22, member 18
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC38A1 solute carrier family 38, member 1

decreased expression

Symbol Name
ADI1 acireductone dioxygenase 1
CCL2 chemokine (C-C motif) ligand 2
CKS2 CDC28 protein kinase regulatory subunit 2
HTRA1 HtrA serine peptidase 1
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2