BRD-K56196992_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

55 genes differentially expressed following the BRD-K56196992_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AQP3 aquaporin 3 (Gill blood group)
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ATF3 activating transcription factor 3
BASP1 brain abundant, membrane attached signal protein 1
C3 complement component 3
CAST calpastatin
CCNG2 cyclin G2
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
COL10A1 collagen, type X, alpha 1
COL1A2 collagen, type I, alpha 2
CX3CR1 chemokine (C-X3-C motif) receptor 1
DDIT4 DNA-damage-inducible transcript 4
DHCR24 24-dehydrocholesterol reductase
DKK3 dickkopf WNT signaling pathway inhibitor 3
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
ELOVL6 ELOVL fatty acid elongase 6
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
FADS1 fatty acid desaturase 1
FADS2 fatty acid desaturase 2
FBN1 fibrillin 1
FDPS farnesyl diphosphate synthase
FHL1 four and a half LIM domains 1
GNG11 guanine nucleotide binding protein (G protein), gamma 11
HES1 hes family bHLH transcription factor 1
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
IDI1 isopentenyl-diphosphate delta isomerase 1
IFI27 interferon, alpha-inducible protein 27
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
INSIG1 insulin induced gene 1
ISG15 ISG15 ubiquitin-like modifier
LDLR low density lipoprotein receptor
MSMO1 methylsterol monooxygenase 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NPY1R neuropeptide Y receptor Y1
PEG10 paternally expressed 10
PLAU plasminogen activator, urokinase
PXDN peroxidasin
RBP4 retinol binding protein 4, plasma
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SGCE sarcoglycan, epsilon
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SQLE squalene epoxidase
TFF3 trefoil factor 3 (intestinal)
THBS2 thrombospondin 2
TUBA1A tubulin, alpha 1a

decreased expression

Symbol Name
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CXCL13 chemokine (C-X-C motif) ligand 13
FOSL1 FOS-like antigen 1
HOXA10 homeobox A10
PLK1 polo-like kinase 1