BRD-K56111351_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

65 genes differentially expressed following the BRD-K56111351_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ARG2 arginase 2
BST2 bone marrow stromal cell antigen 2
COL5A1 collagen, type V, alpha 1
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DPYD dihydropyrimidine dehydrogenase
EMP3 epithelial membrane protein 3
F2RL1 coagulation factor II (thrombin) receptor-like 1
FGFR3 fibroblast growth factor receptor 3
GLIPR1 GLI pathogenesis-related 1
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GSTM3 glutathione S-transferase mu 3 (brain)
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HMOX1 heme oxygenase 1
IFI16 interferon, gamma-inducible protein 16
IFI6 interferon, alpha-inducible protein 6
IL6ST interleukin 6 signal transducer
IQGAP2 IQ motif containing GTPase activating protein 2
LAMB1 laminin, beta 1
LPL lipoprotein lipase
MPPED2 metallophosphoesterase domain containing 2
NEFH neurofilament, heavy polypeptide
P3H2 prolyl 3-hydroxylase 2
PIR pirin (iron-binding nuclear protein)
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SRGN serglycin
STEAP1 six transmembrane epithelial antigen of the prostate 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THBS1 thrombospondin 1
XAF1 XIAP associated factor 1
ZFP36L2 ZFP36 ring finger protein-like 2

decreased expression

Symbol Name
ARID4B AT rich interactive domain 4B (RBP1-like)
CENPE centromere protein E, 312kDa
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLDN3 claudin 3
COL3A1 collagen, type III, alpha 1
CRIP1 cysteine-rich protein 1 (intestinal)
CRIP2 cysteine-rich protein 2
DHRS2 dehydrogenase/reductase (SDR family) member 2
DOCK4 dedicator of cytokinesis 4
DUSP6 dual specificity phosphatase 6
EIF5 eukaryotic translation initiation factor 5
FAM13A family with sequence similarity 13, member A
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HN1 hematological and neurological expressed 1
IGHM immunoglobulin heavy constant mu
KRT7 keratin 7, type II
LSR lipolysis stimulated lipoprotein receptor
MAPK6 mitogen-activated protein kinase 6
MYO5C myosin VC
OAT ornithine aminotransferase
OXA1L oxidase (cytochrome c) assembly 1-like
PCNA proliferating cell nuclear antigen
PIP prolactin-induced protein
POLG2 polymerase (DNA directed), gamma 2, accessory subunit
PROM1 prominin 1
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
SCG5 secretogranin V
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SYBU syntabulin (syntaxin-interacting)
TFPI2 tissue factor pathway inhibitor 2
TUBA1A tubulin, alpha 1a
TXNDC9 thioredoxin domain containing 9
UBE3C ubiquitin protein ligase E3C