BRD-K55473186_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

57 genes differentially expressed following the BRD-K55473186_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADM adrenomedullin
ATF3 activating transcription factor 3
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
C10ORF10 chromosome 10 open reading frame 10
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CXCL10 chemokine (C-X-C motif) ligand 10
FAM69A family with sequence similarity 69, member A
FBN2 fibrillin 2
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
IDO1 indoleamine 2,3-dioxygenase 1
IGFBP5 insulin-like growth factor binding protein 5
IL6R interleukin 6 receptor
IRF1 interferon regulatory factor 1
LPIN1 lipin 1
MME membrane metallo-endopeptidase
NPIPB3 nuclear pore complex interacting protein family, member B3
NVL nuclear VCP-like
PAEP progestagen-associated endometrial protein
PLIN2 perilipin 2
RGCC regulator of cell cycle
RNF24 ring finger protein 24
SNAI2 snail family zinc finger 2
ZNF512B zinc finger protein 512B

decreased expression

Symbol Name
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ARID4B AT rich interactive domain 4B (RBP1-like)
CD320 CD320 molecule
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
E2F2 E2F transcription factor 2
EPS8 epidermal growth factor receptor pathway substrate 8
FKBP10 FK506 binding protein 10, 65 kDa
GATA2 GATA binding protein 2
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IGFBP4 insulin-like growth factor binding protein 4
MGP matrix Gla protein
NQO1 NAD(P)H dehydrogenase, quinone 1
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PLAC8 placenta-specific 8
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
RAD23B RAD23 homolog B (S. cerevisiae)
S100A9 S100 calcium binding protein A9
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SIDT2 SID1 transmembrane family, member 2
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SORD sorbitol dehydrogenase
SOX9 SRY (sex determining region Y)-box 9
TFF1 trefoil factor 1
TGFBI transforming growth factor, beta-induced, 68kDa
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGM2 transglutaminase 2
TM4SF1 transmembrane 4 L six family member 1
TPD52L1 tumor protein D52-like 1
UGCG UDP-glucose ceramide glucosyltransferase
VAMP8 vesicle-associated membrane protein 8
WBSCR22 Williams Beuren syndrome chromosome region 22
WSB2 WD repeat and SOCS box containing 2