BRD-K55187425_ON-01910_MCF7_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

51 genes differentially expressed following the BRD-K55187425_ON-01910_MCF7_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDOA aldolase A, fructose-bisphosphate
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CENPE centromere protein E, 312kDa
CKB creatine kinase, brain
CRELD2 cysteine-rich with EGF-like domains 2
DDIT4 DNA-damage-inducible transcript 4
F13A1 coagulation factor XIII, A1 polypeptide
FOSL1 FOS-like antigen 1
HACD1 3-hydroxyacyl-CoA dehydratase 1
HIST1H2AC histone cluster 1, H2ac
HIST1H2BG histone cluster 1, H2bg
HIST2H2BE histone cluster 2, H2be
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
PALMD palmdelphin
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor
PEG3 paternally expressed 3
PRSS8 protease, serine, 8
SLC35F2 solute carrier family 35, member F2
SVIL supervillin
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TMEM45A transmembrane protein 45A
TRIM16 tripartite motif containing 16
VDAC1 voltage-dependent anion channel 1
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
CD24 CD24 molecule
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CGRRF1 cell growth regulator with ring finger domain 1
CHRDL1 chordin-like 1
CPE carboxypeptidase E
CSRP2 cysteine and glycine-rich protein 2
CXCL14 chemokine (C-X-C motif) ligand 14
CYTL1 cytokine-like 1
EPHA3 EPH receptor A3
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FGL2 fibrinogen-like 2
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
IL17RB interleukin 17 receptor B
ITM2A integral membrane protein 2A
MERTK MER proto-oncogene, tyrosine kinase
PCNA proliferating cell nuclear antigen
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
RNASE4 ribonuclease, RNase A family, 4
SNRPB small nuclear ribonucleoprotein polypeptides B and B1
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae)
TBCB tubulin folding cofactor B
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TMSB15A thymosin beta 15a
TP53 tumor protein p53