BRD-K55187425_ON-01910_HCC515_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

54 genes differentially expressed following the BRD-K55187425_ON-01910_HCC515_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BEX1 brain expressed, X-linked 1
CCNA2 cyclin A2
CCNF cyclin F
CDC42BPB CDC42 binding protein kinase beta (DMPK-like)
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CXCL8 chemokine (C-X-C motif) ligand 8
DKK3 dickkopf WNT signaling pathway inhibitor 3
ENC1 ectodermal-neural cortex 1 (with BTB domain)
FBN1 fibrillin 1
FHL1 four and a half LIM domains 1
FLNB filamin B, beta
FSTL1 follistatin-like 1
GLIPR1 GLI pathogenesis-related 1
KIF14 kinesin family member 14
KIF20A kinesin family member 20A
KIF5C kinesin family member 5C
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MTA1 metastasis associated 1
PBX3 pre-B-cell leukemia homeobox 3
RHOB ras homolog family member B
SORBS1 sorbin and SH3 domain containing 1
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
THBS1 thrombospondin 1
TSPAN8 tetraspanin 8
VCL vinculin

decreased expression

Symbol Name
ACD adrenocortical dysplasia homolog (mouse)
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
C8ORF4 chromosome 8 open reading frame 4
CA12 carbonic anhydrase XII
CDH3 cadherin 3, type 1, P-cadherin (placental)
CTSH cathepsin H
FAM134B family with sequence similarity 134, member B
FBXO21 F-box protein 21
FCGBP Fc fragment of IgG binding protein
FGFR2 fibroblast growth factor receptor 2
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GOLGA8B golgin A8 family, member B
GSTA4 glutathione S-transferase alpha 4
HACD3 3-hydroxyacyl-CoA dehydratase 3
JCHAIN joining chain of multimeric IgA and IgM
KYNU kynureninase
LBH limb bud and heart development
LCN2 lipocalin 2
LYZ lysozyme
MMP7 matrix metallopeptidase 7
MXRA5 matrix-remodelling associated 5
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
OLFM4 olfactomedin 4
PFN2 profilin 2
SEPP1 selenoprotein P, plasma, 1
SLBP stem-loop binding protein
STAB1 stabilin 1
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)