BRD-K55187425_ON-01910_HA1E_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

108 genes differentially expressed following the BRD-K55187425_ON-01910_HA1E_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BAG3 BCL2-associated athanogene 3
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
COL10A1 collagen, type X, alpha 1
CSRP1 cysteine and glycine-rich protein 1
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL8 chemokine (C-X-C motif) ligand 8
DUSP6 dual specificity phosphatase 6
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
ENC1 ectodermal-neural cortex 1 (with BTB domain)
EREG epiregulin
FABP4 fatty acid binding protein 4, adipocyte
FKBP11 FK506 binding protein 11, 19 kDa
FOSL1 FOS-like antigen 1
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5
H2BFS H2B histone family, member S (pseudogene)
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HIST1H2BE histone cluster 1, H2be
HIST1H2BF histone cluster 1, H2bf
HIST1H2BG histone cluster 1, H2bg
HIST1H2BK histone cluster 1, H2bk
IGHM immunoglobulin heavy constant mu
IGKC immunoglobulin kappa constant
IGKV1-5 immunoglobulin kappa variable 1-5
IGL immunoglobulin lambda locus
LAMA4 laminin, alpha 4
LMO2 LIM domain only 2 (rhombotin-like 1)
LTF lactotransferrin
MECOM MDS1 and EVI1 complex locus
MMP1 matrix metallopeptidase 1
PNP purine nucleoside phosphorylase
POSTN periostin, osteoblast specific factor
POU2AF1 POU class 2 associating factor 1
PTX3 pentraxin 3, long
STX1A syntaxin 1A (brain)
TEX10 testis expressed 10
TF transferrin
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
WT1 Wilms tumor 1

decreased expression

Symbol Name
ACPP acid phosphatase, prostate
AKR1C3 aldo-keto reductase family 1, member C3
BEX1 brain expressed, X-linked 1
C14ORF1 chromosome 14 open reading frame 1
C14ORF132 chromosome 14 open reading frame 132
CADM1 cell adhesion molecule 1
CALD1 caldesmon 1
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CD24 CD24 molecule
CDC25B cell division cycle 25B
CDK1 cyclin-dependent kinase 1
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CSRP2 cysteine and glycine-rich protein 2
CXCL12 chemokine (C-X-C motif) ligand 12
DEGS1 delta(4)-desaturase, sphingolipid 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DST dystonin
EPHA3 EPH receptor A3
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FLNA filamin A, alpha
FLRT3 fibronectin leucine rich transmembrane protein 3
FZD7 frizzled class receptor 7
GPNMB glycoprotein (transmembrane) nmb
GSTM3 glutathione S-transferase mu 3 (brain)
GULP1 GULP, engulfment adaptor PTB domain containing 1
HLA-B major histocompatibility complex, class I, B
HOXA10 homeobox A10
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IGFBP3 insulin-like growth factor binding protein 3
IGFBP5 insulin-like growth factor binding protein 5
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
LUM lumican
MAP1B microtubule-associated protein 1B
MATN2 matrilin 2
MFAP4 microfibrillar-associated protein 4
MID1 midline 1
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MSMO1 methylsterol monooxygenase 1
MYL9 myosin, light chain 9, regulatory
MYLK myosin light chain kinase
NAV2 neuron navigator 2
NDRG1 N-myc downstream regulated 1
NME4 NME/NM23 nucleoside diphosphate kinase 4
NREP neuronal regeneration related protein
OLFML3 olfactomedin-like 3
PENK proenkephalin
PLCB4 phospholipase C, beta 4
PMEPA1 prostate transmembrane protein, androgen induced 1
PTN pleiotrophin
PTP4A3 protein tyrosine phosphatase type IVA, member 3
QPCT glutaminyl-peptide cyclotransferase
SFRP1 secreted frizzled-related protein 1
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SPINT2 serine peptidase inhibitor, Kunitz type, 2
SRRM2 serine/arginine repetitive matrix 2
SV2A synaptic vesicle glycoprotein 2A
SYT1 synaptotagmin I
TACSTD2 tumor-associated calcium signal transducer 2
TBX3 T-box 3
TM7SF2 transmembrane 7 superfamily member 2
TOP2A topoisomerase (DNA) II alpha 170kDa
TPD52L1 tumor protein D52-like 1
WDTC1 WD and tetratricopeptide repeats 1
WFDC2 WAP four-disulfide core domain 2