BRD-K55187425_ON-01910_A375_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

71 genes differentially expressed following the BRD-K55187425_ON-01910_A375_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADRB2 adrenoceptor beta 2, surface
ALCAM activated leukocyte cell adhesion molecule
BAG3 BCL2-associated athanogene 3
CDC25A cell division cycle 25A
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
DDB2 damage-specific DNA binding protein 2, 48kDa
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
FDXR ferredoxin reductase
FHL2 four and a half LIM domains 2
FOSL1 FOS-like antigen 1
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GAS6 growth arrest-specific 6
GFOD1 glucose-fructose oxidoreductase domain containing 1
H2BFS H2B histone family, member S (pseudogene)
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HIST1H2BF histone cluster 1, H2bf
HIST1H2BK histone cluster 1, H2bk
KRT14 keratin 14, type I
KRT17 keratin 17, type I
KRT7 keratin 7, type II
LEFTY1 left-right determination factor 1
LMO3 LIM domain only 3 (rhombotin-like 2)
MFAP5 microfibrillar associated protein 5
MICALL1 MICAL-like 1
MT1E metallothionein 1E
MXRA7 matrix-remodelling associated 7
PEG3 paternally expressed 3
PIH1D1 PIH1 domain containing 1
PROM1 prominin 1
REXO2 RNA exonuclease 2
RGS2 regulator of G-protein signaling 2
RPS27L ribosomal protein S27-like
RUNX3 runt-related transcription factor 3
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SESN1 sestrin 1
SIDT2 SID1 transmembrane family, member 2
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SOCS2 suppressor of cytokine signaling 2
TRIM22 tripartite motif containing 22
ZW10 zw10 kinetochore protein

decreased expression

Symbol Name
BMP4 bone morphogenetic protein 4
CAPZB capping protein (actin filament) muscle Z-line, beta
CD52 CD52 molecule
CFI complement factor I
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLU clusterin
CXCL5 chemokine (C-X-C motif) ligand 5
DCK deoxycytidine kinase
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
LEF1 lymphoid enhancer-binding factor 1
LTBP1 latent transforming growth factor beta binding protein 1
MDFIC MyoD family inhibitor domain containing
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
NR2F1 nuclear receptor subfamily 2, group F, member 1
NREP neuronal regeneration related protein
NRP1 neuropilin 1
PPIC peptidylprolyl isomerase C (cyclophilin C)
PRDX2 peroxiredoxin 2
RAD23B RAD23 homolog B (S. cerevisiae)
RHOBTB1 Rho-related BTB domain containing 1
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
S100A9 S100 calcium binding protein A9
SRGN serglycin
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
TMSB15A thymosin beta 15a
TTC3 tetratricopeptide repeat domain 3
YME1L1 YME1-like 1 ATPase
ZNF117 zinc finger protein 117