BRD-K55116708_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

83 genes differentially expressed following the BRD-K55116708_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ADGRG6 adhesion G protein-coupled receptor G6
ADIRF adipogenesis regulatory factor
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ANPEP alanyl (membrane) aminopeptidase
ANXA1 annexin A1
C10ORF10 chromosome 10 open reading frame 10
CCL20 chemokine (C-C motif) ligand 20
CD36 CD36 molecule (thrombospondin receptor)
CDH19 cadherin 19, type 2
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CIRBP cold inducible RNA binding protein
CKLF chemokine-like factor
CYBA cytochrome b-245, alpha polypeptide
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DHRS3 dehydrogenase/reductase (SDR family) member 3
EIF5A eukaryotic translation initiation factor 5A
EPS8 epidermal growth factor receptor pathway substrate 8
FKBP1B FK506 binding protein 1B, 12.6 kDa
FTH1 ferritin, heavy polypeptide 1
GALC galactosylceramidase
GDF15 growth differentiation factor 15
GPX2 glutathione peroxidase 2
HBB hemoglobin, beta
HIST1H1C histone cluster 1, H1c
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IER3 immediate early response 3
IGLL1 immunoglobulin lambda-like polypeptide 1
IL1RN interleukin 1 receptor antagonist
ITGA6 integrin, alpha 6
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
KRT18 keratin 18, type I
LGALS1 lectin, galactoside-binding, soluble, 1
LGALS2 lectin, galactoside-binding, soluble, 2
LGALS3 lectin, galactoside-binding, soluble, 3
LYZ lysozyme
MCAM melanoma cell adhesion molecule
MMP1 matrix metallopeptidase 1
MYOF myoferlin
NPTX2 neuronal pentraxin II
NQO1 NAD(P)H dehydrogenase, quinone 1
PLAC8 placenta-specific 8
PLAT plasminogen activator, tissue
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRKCA protein kinase C, alpha
RCAN1 regulator of calcineurin 1
RGS2 regulator of G-protein signaling 2
RTN1 reticulon 1
S100A4 S100 calcium binding protein A4
SFN stratifin
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMAD3 SMAD family member 3
SOX9 SRY (sex determining region Y)-box 9
SPAG16 sperm associated antigen 16
SPINK1 serine peptidase inhibitor, Kazal type 1
SRGN serglycin
TFRC transferrin receptor
TGFBI transforming growth factor, beta-induced, 68kDa
THBS1 thrombospondin 1
TM4SF1 transmembrane 4 L six family member 1
TST thiosulfate sulfurtransferase (rhodanese)

decreased expression

Symbol Name
ASPN asporin
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CXCL13 chemokine (C-X-C motif) ligand 13
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
LTF lactotransferrin
MRPS2 mitochondrial ribosomal protein S2
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
PWP1 PWP1 homolog (S. cerevisiae)
PYCARD PYD and CARD domain containing
RHOBTB3 Rho-related BTB domain containing 3
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SLPI secretory leukocyte peptidase inhibitor
TCF4 transcription factor 4
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
UBE3A ubiquitin protein ligase E3A