BRD-K55071917_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

43 genes differentially expressed following the BRD-K55071917_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1C3 aldo-keto reductase family 1, member C3
ASNS asparagine synthetase (glutamine-hydrolyzing)
CBS cystathionine-beta-synthase
CD163 CD163 molecule
CLU clusterin
DDIT4 DNA-damage-inducible transcript 4
ERBB3 erb-b2 receptor tyrosine kinase 3
F13A1 coagulation factor XIII, A1 polypeptide
HIST1H2AC histone cluster 1, H2ac
HIST2H2BE histone cluster 2, H2be
HMOX1 heme oxygenase 1
LRRC17 leucine rich repeat containing 17
LY96 lymphocyte antigen 96
MVP major vault protein
NUPR1 nuclear protein, transcriptional regulator, 1
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PHGDH phosphoglycerate dehydrogenase
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SELENBP1 selenium binding protein 1
SEPP1 selenoprotein P, plasma, 1
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SQSTM1 sequestosome 1
TACSTD2 tumor-associated calcium signal transducer 2
TRIM16 tripartite motif containing 16
TSC22D3 TSC22 domain family, member 3
TSKU tsukushi, small leucine rich proteoglycan
VAT1 vesicle amine transport 1
VSIG4 V-set and immunoglobulin domain containing 4

decreased expression

Symbol Name
ACAT2 acetyl-CoA acetyltransferase 2
CCNE2 cyclin E2
CDC42 cell division cycle 42
CPE carboxypeptidase E
FGF13 fibroblast growth factor 13
FHL1 four and a half LIM domains 1
KIF14 kinesin family member 14
MMP9 matrix metallopeptidase 9
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLN phospholamban
RFC5 replication factor C (activator 1) 5, 36.5kDa
RRM2 ribonucleotide reductase M2
SPINK1 serine peptidase inhibitor, Kazal type 1