BRD-K54997624_BYL719_SKBR3_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

55 genes differentially expressed following the BRD-K54997624_BYL719_SKBR3_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTA2 actin, alpha 2, smooth muscle, aorta
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADGRA3 adhesion G protein-coupled receptor A3
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ARID5B AT rich interactive domain 5B (MRF1-like)
BHLHE40 basic helix-loop-helix family, member e40
C10ORF10 chromosome 10 open reading frame 10
COL6A1 collagen, type VI, alpha 1
CPE carboxypeptidase E
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
FHL1 four and a half LIM domains 1
HDGFRP3 hepatoma-derived growth factor, related protein 3
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
INHBA inhibin, beta A
KDM5D lysine (K)-specific demethylase 5D
KIAA0355 KIAA0355
LAMA3 laminin, alpha 3
LCN2 lipocalin 2
LGALS3 lectin, galactoside-binding, soluble, 3
MAMLD1 mastermind-like domain containing 1
NPY neuropeptide Y
RAB31 RAB31, member RAS oncogene family
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RGS2 regulator of G-protein signaling 2
RHOB ras homolog family member B
RPS4Y1 ribosomal protein S4, Y-linked 1
STC2 stanniocalcin 2
TPD52L1 tumor protein D52-like 1
TSPAN13 tetraspanin 13
VIM vimentin
ZFAND5 zinc finger, AN1-type domain 5
ZNF274 zinc finger protein 274
ZSCAN18 zinc finger and SCAN domain containing 18

decreased expression

Symbol Name
ADRB2 adrenoceptor beta 2, surface
AQP3 aquaporin 3 (Gill blood group)
CCNE2 cyclin E2
CXCL11 chemokine (C-X-C motif) ligand 11
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
JADE2 jade family PHD finger 2
LYN LYN proto-oncogene, Src family tyrosine kinase
PCSK6 proprotein convertase subtilisin/kexin type 6
PDHX pyruvate dehydrogenase complex, component X
PUF60 poly-U binding splicing factor 60KDa
SORD sorbitol dehydrogenase
SPRED2 sprouty-related, EVH1 domain containing 2
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TMEM45A transmembrane protein 45A
XIST X inactive specific transcript (non-protein coding)