BRD-K54997624_BYL719_HT29_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

80 genes differentially expressed following the BRD-K54997624_BYL719_HT29_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANKRD10 ankyrin repeat domain 10
ATP9A ATPase, class II, type 9A
C1ORF115 chromosome 1 open reading frame 115
C6ORF62 chromosome 6 open reading frame 62
CAPN2 calpain 2, (m/II) large subunit
COBL cordon-bleu WH2 repeat protein
COLEC12 collectin sub-family member 12
CYTH1 cytohesin 1
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DAPK1 death-associated protein kinase 1
DCLK1 doublecortin-like kinase 1
DPYSL2 dihydropyrimidinase-like 2
DSP desmoplakin
EDN1 endothelin 1
EIF4B eukaryotic translation initiation factor 4B
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
FHL1 four and a half LIM domains 1
FOXO4 forkhead box O4
HIST1H2BD histone cluster 1, H2bd
HLA-B major histocompatibility complex, class I, B
HLA-E major histocompatibility complex, class I, E
LOXL1 lysyl oxidase-like 1
MFSD10 major facilitator superfamily domain containing 10
MTSS1 metastasis suppressor 1
MTUS1 microtubule associated tumor suppressor 1
MVP major vault protein
MXI1 MAX interactor 1, dimerization protein
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
PAM peptidylglycine alpha-amidating monooxygenase
PDGFRL platelet-derived growth factor receptor-like
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha
PNMA2 paraneoplastic Ma antigen 2
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PTPRK protein tyrosine phosphatase, receptor type, K
RAB25 RAB25, member RAS oncogene family
RAB4A RAB4A, member RAS oncogene family
REEP1 receptor accessory protein 1
RHOBTB3 Rho-related BTB domain containing 3
RPS4Y1 ribosomal protein S4, Y-linked 1
RSRP1 arginine/serine-rich protein 1
SH3YL1 SH3 and SYLF domain containing 1
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SOX4 SRY (sex determining region Y)-box 4
TCAF1 TRPM8 channel-associated factor 1
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TOX thymocyte selection-associated high mobility group box
TPP1 tripeptidyl peptidase I
TXNIP thioredoxin interacting protein
WLS wntless Wnt ligand secretion mediator

decreased expression

Symbol Name
AURKA aurora kinase A
CIAPIN1 cytokine induced apoptosis inhibitor 1
COL4A5 collagen, type IV, alpha 5
CSTA cystatin A (stefin A)
CXCR4 chemokine (C-X-C motif) receptor 4
DEPDC1 DEP domain containing 1
EREG epiregulin
G0S2 G0/G1 switch 2
HSPA14 heat shock 70kDa protein 14
HSPA2 heat shock 70kDa protein 2
HSPA4L heat shock 70kDa protein 4-like
IL13RA2 interleukin 13 receptor, alpha 2
KLHL7 kelch-like family member 7
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MYLK myosin light chain kinase
NRIP1 nuclear receptor interacting protein 1
ODC1 ornithine decarboxylase 1
OIP5 Opa interacting protein 5
PLAU plasminogen activator, urokinase
PLK1 polo-like kinase 1
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PSAT1 phosphoserine aminotransferase 1
RGCC regulator of cell cycle
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
TM4SF1 transmembrane 4 L six family member 1
UPP1 uridine phosphorylase 1
XIST X inactive specific transcript (non-protein coding)