BRD-K54997624_BYL719_BT20_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

56 genes differentially expressed following the BRD-K54997624_BYL719_BT20_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
ARID5B AT rich interactive domain 5B (MRF1-like)
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CHIC2 cysteine-rich hydrophobic domain 2
EPS8 epidermal growth factor receptor pathway substrate 8
ERBB3 erb-b2 receptor tyrosine kinase 3
GRAMD3 GRAM domain containing 3
IDS iduronate 2-sulfatase
MGP matrix Gla protein
MXI1 MAX interactor 1, dimerization protein
MYO6 myosin VI
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PSPH phosphoserine phosphatase
QKI QKI, KH domain containing, RNA binding
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RGS1 regulator of G-protein signaling 1
TM4SF1 transmembrane 4 L six family member 1
USP6NL USP6 N-terminal like
VAV3 vav 3 guanine nucleotide exchange factor
WWP1 WW domain containing E3 ubiquitin protein ligase 1

decreased expression

Symbol Name
CA12 carbonic anhydrase XII
CCL19 chemokine (C-C motif) ligand 19
CD24 CD24 molecule
CKB creatine kinase, brain
CLCA2 chloride channel accessory 2
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL9 chemokine (C-X-C motif) ligand 9
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP4 dual specificity phosphatase 4
FABP4 fatty acid binding protein 4, adipocyte
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FOSL1 FOS-like antigen 1
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7
GATA2 GATA binding protein 2
GBP1 guanylate binding protein 1, interferon-inducible
GCH1 GTP cyclohydrolase 1
HHEX hematopoietically expressed homeobox
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IDO1 indoleamine 2,3-dioxygenase 1
KRT13 keratin 13, type I
KYNU kynureninase
LTF lactotransferrin
MALL mal, T-cell differentiation protein-like
MAT2A methionine adenosyltransferase II, alpha
MTSS1 metastasis suppressor 1
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
PNP purine nucleoside phosphorylase
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
S100A12 S100 calcium binding protein A12
SORBS2 sorbin and SH3 domain containing 2
TFF3 trefoil factor 3 (intestinal)