BRD-K54906270_-666_ASC_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

116 genes differentially expressed following the BRD-K54906270_-666_ASC_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALCAM activated leukocyte cell adhesion molecule
ANXA5 annexin A5
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
BEX1 brain expressed, X-linked 1
BST2 bone marrow stromal cell antigen 2
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
COL9A3 collagen, type IX, alpha 3
COTL1 coactosin-like F-actin binding protein 1
CRIP1 cysteine-rich protein 1 (intestinal)
CTGF connective tissue growth factor
CXCL14 chemokine (C-X-C motif) ligand 14
CXCL8 chemokine (C-X-C motif) ligand 8
CYR61 cysteine-rich, angiogenic inducer, 61
DKK1 dickkopf WNT signaling pathway inhibitor 1
DLC1 DLC1 Rho GTPase activating protein
EMP3 epithelial membrane protein 3
FKBP1B FK506 binding protein 1B, 12.6 kDa
GNAS GNAS complex locus
GOLGA8A golgin A8 family, member A
GRAMD3 GRAM domain containing 3
GSTM3 glutathione S-transferase mu 3 (brain)
HAPLN1 hyaluronan and proteoglycan link protein 1
HOXC6 homeobox C6
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KRT7 keratin 7, type II
LAMP5 lysosomal-associated membrane protein family, member 5
LMO2 LIM domain only 2 (rhombotin-like 1)
LOX lysyl oxidase
LTF lactotransferrin
MAPT microtubule-associated protein tau
MT1E metallothionein 1E
MT1F metallothionein 1F
NQO1 NAD(P)H dehydrogenase, quinone 1
PLAC8 placenta-specific 8
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PROM1 prominin 1
PTX3 pentraxin 3, long
RAB4A RAB4A, member RAS oncogene family
RGS4 regulator of G-protein signaling 4
RHOBTB3 Rho-related BTB domain containing 3
RPS27L ribosomal protein S27-like
SFRP1 secreted frizzled-related protein 1
SGK1 serum/glucocorticoid regulated kinase 1
SH3BP4 SH3-domain binding protein 4
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC43A3 solute carrier family 43, member 3
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFRC transferrin receptor
TICAM1 toll-like receptor adaptor molecule 1
TJP2 tight junction protein 2
TMEM243 transmembrane protein 243, mitochondrial
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TUBB3 tubulin, beta 3 class III
TXNL4B thioredoxin-like 4B

decreased expression

Symbol Name
ACTA1 actin, alpha 1, skeletal muscle
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
ALOX5 arachidonate 5-lipoxygenase
ALOX5AP arachidonate 5-lipoxygenase-activating protein
APOD apolipoprotein D
BASP1 brain abundant, membrane attached signal protein 1
BCHE butyrylcholinesterase
C5AR1 complement component 5a receptor 1
CCND2 cyclin D2
CD52 CD52 molecule
CFD complement factor D (adipsin)
CKM creatine kinase, muscle
CLEC5A C-type lectin domain family 5, member A
CLIC5 chloride intracellular channel 5
CX3CR1 chemokine (C-X3-C motif) receptor 1
DES desmin
DPT dermatopontin
E2F2 E2F transcription factor 2
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
F13A1 coagulation factor XIII, A1 polypeptide
FBN2 fibrillin 2
FXYD6 FXYD domain containing ion transport regulator 6
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HOMER3 homer scaffolding protein 3
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HSPB3 heat shock 27kDa protein 3
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
KLF5 Kruppel-like factor 5 (intestinal)
KLK5 kallikrein-related peptidase 5
KRT23 keratin 23, type I
LDB3 LIM domain binding 3
LGALS3 lectin, galactoside-binding, soluble, 3
LGALS4 lectin, galactoside-binding, soluble, 4
MAP7 microtubule-associated protein 7
MME membrane metallo-endopeptidase
MYOT myotilin
NEB nebulin
NPIPB3 nuclear pore complex interacting protein family, member B3
PDLIM3 PDZ and LIM domain 3
PLN phospholamban
PTN pleiotrophin
PTP4A3 protein tyrosine phosphatase type IVA, member 3
RAB25 RAB25, member RAS oncogene family
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
S100P S100 calcium binding protein P
SDC1 syndecan 1
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SPARCL1 SPARC-like 1 (hevin)
TDO2 tryptophan 2,3-dioxygenase
THY1 Thy-1 cell surface antigen
TNNT1 troponin T type 1 (skeletal, slow)
TRD T cell receptor delta locus
TRDV3 T cell receptor delta variable 3
VEGFA vascular endothelial growth factor A
WT1 Wilms tumor 1