BRD-K54906270_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

29 genes differentially expressed following the BRD-K54906270_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
CA1 carbonic anhydrase I
LAT2 linker for activation of T cells family, member 2
RGS2 regulator of G-protein signaling 2
SIAH2 siah E3 ubiquitin protein ligase 2

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRF5 adhesion G protein-coupled receptor F5
ALDOB aldolase B, fructose-bisphosphate
ANXA1 annexin A1
AZU1 azurocidin 1
CALD1 caldesmon 1
CFD complement factor D (adipsin)
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CLC Charcot-Leyden crystal galectin
CPE carboxypeptidase E
CPT1A carnitine palmitoyltransferase 1A (liver)
CRISP3 cysteine-rich secretory protein 3
DEFA4 defensin, alpha 4, corticostatin
DHRS2 dehydrogenase/reductase (SDR family) member 2
ELANE elastase, neutrophil expressed
FZD6 frizzled class receptor 6
IGFBP7 insulin-like growth factor binding protein 7
MFAP5 microfibrillar associated protein 5
MPO myeloperoxidase
MYH11 myosin, heavy chain 11, smooth muscle
PLS3 plastin 3
PRTN3 proteinase 3
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
THBS1 thrombospondin 1
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)