BRD-K54771420_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

26 genes differentially expressed following the BRD-K54771420_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ANXA3 annexin A3
BAZ1A bromodomain adjacent to zinc finger domain, 1A
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CXCL8 chemokine (C-X-C motif) ligand 8
IGHM immunoglobulin heavy constant mu
LTF lactotransferrin
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADM adrenomedullin
C1QA complement component 1, q subcomponent, A chain
C1QB complement component 1, q subcomponent, B chain
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CCND2 cyclin D2
CD163 CD163 molecule
CPB1 carboxypeptidase B1 (tissue)
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL9 chemokine (C-X-C motif) ligand 9
HOPX HOP homeobox
IGFBP5 insulin-like growth factor binding protein 5
LMO3 LIM domain only 3 (rhombotin-like 2)
NCAM1 neural cell adhesion molecule 1
PEG10 paternally expressed 10
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
SEPP1 selenoprotein P, plasma, 1
SHB Src homology 2 domain containing adaptor protein B
SPARCL1 SPARC-like 1 (hevin)