BRD-K54606188_(+)-JQ1_HA1E_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

112 genes differentially expressed following the BRD-K54606188_(+)-JQ1_HA1E_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
AKR1C3 aldo-keto reductase family 1, member C3
ASMTL acetylserotonin O-methyltransferase-like
BLNK B-cell linker
BTG1 B-cell translocation gene 1, anti-proliferative
BTG2 BTG family, member 2
CADM1 cell adhesion molecule 1
CD52 CD52 molecule
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CLCA1 chloride channel accessory 1
COL13A1 collagen, type XIII, alpha 1
CPA3 carboxypeptidase A3 (mast cell)
CXADR coxsackie virus and adenovirus receptor
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
EZR ezrin
FOLR1 folate receptor 1 (adult)
H2BFS H2B histone family, member S (pseudogene)
HEBP1 heme binding protein 1
HIST1H1C histone cluster 1, H1c
HIST1H2BD histone cluster 1, H2bd
HIST1H2BK histone cluster 1, H2bk
HOXA5 homeobox A5
IGHD immunoglobulin heavy constant delta
JUN jun proto-oncogene
KIF2C kinesin family member 2C
KLF4 Kruppel-like factor 4 (gut)
LTBP1 latent transforming growth factor beta binding protein 1
MAN2A1 mannosidase, alpha, class 2A, member 1
MEF2C myocyte enhancer factor 2C
METTL7A methyltransferase like 7A
MUC2 mucin 2, oligomeric mucus/gel-forming
NBPF10 neuroblastoma breakpoint family, member 10
NID2 nidogen 2 (osteonidogen)
NTS neurotensin
PAX5 paired box 5
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PSIP1 PC4 and SFRS1 interacting protein 1
REG1A regenerating islet-derived 1 alpha
RGS2 regulator of G-protein signaling 2
RPS4Y1 ribosomal protein S4, Y-linked 1
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SEPP1 selenoprotein P, plasma, 1
SKAP2 src kinase associated phosphoprotein 2
SPON1 spondin 1, extracellular matrix protein
TOX3 TOX high mobility group box family member 3
TXNIP thioredoxin interacting protein
VNN1 vanin 1
ZNF131 zinc finger protein 131

decreased expression

Symbol Name
ADGRE5 adhesion G protein-coupled receptor E5
ALCAM activated leukocyte cell adhesion molecule
ANXA3 annexin A3
APOD apolipoprotein D
AQP3 aquaporin 3 (Gill blood group)
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BCAT1 branched chain amino-acid transaminase 1, cytosolic
CBR3 carbonyl reductase 3
CCL2 chemokine (C-C motif) ligand 2
CD44 CD44 molecule (Indian blood group)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHI3L2 chitinase 3-like 2
CST1 cystatin SN
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL5 chemokine (C-X-C motif) ligand 5
CXCL8 chemokine (C-X-C motif) ligand 8
CXCL9 chemokine (C-X-C motif) ligand 9
CYTH1 cytohesin 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
DOCK10 dedicator of cytokinesis 10
EDN1 endothelin 1
EGF epidermal growth factor
FABP7 fatty acid binding protein 7, brain
FAM129A family with sequence similarity 129, member A
FOSL1 FOS-like antigen 1
GBP1 guanylate binding protein 1, interferon-inducible
GBP2 guanylate binding protein 2, interferon-inducible
GRIA2 glutamate receptor, ionotropic, AMPA 2
ICAM1 intercellular adhesion molecule 1
IFRD2 interferon-related developmental regulator 2
IGFBP3 insulin-like growth factor binding protein 3
IL32 interleukin 32
ISG20 interferon stimulated exonuclease gene 20kDa
JMJD6 jumonji domain containing 6
KRT17 keratin 17, type I
KRT6B keratin 6B, type II
LIMCH1 LIM and calponin homology domains 1
LOX lysyl oxidase
MAPK13 mitogen-activated protein kinase 13
MYBPC1 myosin binding protein C, slow type
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NMB neuromedin B
PDLIM5 PDZ and LIM domain 5
PLCB4 phospholipase C, beta 4
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PYCR1 pyrroline-5-carboxylate reductase 1
S100B S100 calcium binding protein B
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SLPI secretory leukocyte peptidase inhibitor
SORBS2 sorbin and SH3 domain containing 2
SORBS3 sorbin and SH3 domain containing 3
SOX9 SRY (sex determining region Y)-box 9
SRPX2 sushi-repeat containing protein, X-linked 2
STC2 stanniocalcin 2
TACSTD2 tumor-associated calcium signal transducer 2
TARP TCR gamma alternate reading frame protein
TM4SF1 transmembrane 4 L six family member 1
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
XBP1 X-box binding protein 1
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1