BRD-K54330070_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

90 genes differentially expressed following the BRD-K54330070_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADAMDEC1 ADAM-like, decysin 1
ANKRD10 ankyrin repeat domain 10
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
CALR calreticulin
CAST calpastatin
CCL20 chemokine (C-C motif) ligand 20
CCL5 chemokine (C-C motif) ligand 5
CD44 CD44 molecule (Indian blood group)
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CLCA4 chloride channel accessory 4
COL11A1 collagen, type XI, alpha 1
CORO1A coronin, actin binding protein, 1A
CP ceruloplasmin (ferroxidase)
CTBP2 C-terminal binding protein 2
DUSP5 dual specificity phosphatase 5
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5
HSPA13 heat shock protein 70kDa family, member 13
HYOU1 hypoxia up-regulated 1
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
IGKC immunoglobulin kappa constant
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV4-1 immunoglobulin kappa variable 4-1
IGL immunoglobulin lambda locus
IGLJ3 immunoglobulin lambda joining 3
ITM2C integral membrane protein 2C
JCHAIN joining chain of multimeric IgA and IgM
KRT19 keratin 19, type I
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MRPS16 mitochondrial ribosomal protein S16
MZB1 marginal zone B and B1 cell-specific protein
NPTX2 neuronal pentraxin II
POSTN periostin, osteoblast specific factor
RAB38 RAB38, member RAS oncogene family
RGCC regulator of cell cycle
SCGB2A1 secretoglobin, family 2A, member 1
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SEPP1 selenoprotein P, plasma, 1
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SNX7 sorting nexin 7
SULF1 sulfatase 1
TGFB1I1 transforming growth factor beta 1 induced transcript 1
THBS2 thrombospondin 2
TIMP3 TIMP metallopeptidase inhibitor 3
TNFRSF17 tumor necrosis factor receptor superfamily, member 17
VEGFA vascular endothelial growth factor A
XIST X inactive specific transcript (non-protein coding)
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
ZNF395 zinc finger protein 395

decreased expression

Symbol Name
AKAP12 A kinase (PRKA) anchor protein 12
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CLDN18 claudin 18
CRISP3 cysteine-rich secretory protein 3
CSTA cystatin A (stefin A)
CXCL5 chemokine (C-X-C motif) ligand 5
CXCL8 chemokine (C-X-C motif) ligand 8
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DEPTOR DEP domain containing MTOR-interacting protein
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
F5 coagulation factor V (proaccelerin, labile factor)
FBP1 fructose-1,6-bisphosphatase 1
GNG11 guanine nucleotide binding protein (G protein), gamma 11
HOMER1 homer scaffolding protein 1
IGFBP6 insulin-like growth factor binding protein 6
KRT14 keratin 14, type I
LTF lactotransferrin
MAN1C1 mannosidase, alpha, class 1C, member 1
MEGF9 multiple EGF-like-domains 9
MGP matrix Gla protein
NFIB nuclear factor I/B
NPY1R neuropeptide Y receptor Y1
NRN1 neuritin 1
OXA1L oxidase (cytochrome c) assembly 1-like
PHKA1 phosphorylase kinase, alpha 1 (muscle)
PLBD1 phospholipase B domain containing 1
RET ret proto-oncogene
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SFRP1 secreted frizzled-related protein 1
SKAP2 src kinase associated phosphoprotein 2
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
STEAP3 STEAP family member 3, metalloreductase
TBX2 T-box 2
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TGFBI transforming growth factor, beta-induced, 68kDa
TSPAN8 tetraspanin 8
TSPYL5 TSPY-like 5