BRD-K54285697_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

61 genes differentially expressed following the BRD-K54285697_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
BAX BCL2-associated X protein
BEX1 brain expressed, X-linked 1
CD163 CD163 molecule
CFD complement factor D (adipsin)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CKAP4 cytoskeleton-associated protein 4
CLC Charcot-Leyden crystal galectin
CPE carboxypeptidase E
DDIT4 DNA-damage-inducible transcript 4
F13A1 coagulation factor XIII, A1 polypeptide
FAM129A family with sequence similarity 129, member A
FCGBP Fc fragment of IgG binding protein
GNAS GNAS complex locus
IFITM1 interferon induced transmembrane protein 1
LYZ lysozyme
MMP9 matrix metallopeptidase 9
NCAM1 neural cell adhesion molecule 1
PHGDH phosphoglycerate dehydrogenase
SOX9 SRY (sex determining region Y)-box 9
STC1 stanniocalcin 1
TSKU tsukushi, small leucine rich proteoglycan

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ACPP acid phosphatase, prostate
ADI1 acireductone dioxygenase 1
AMD1 adenosylmethionine decarboxylase 1
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
ARMT1 acidic residue methyltransferase 1
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
CAV1 caveolin 1, caveolae protein, 22kDa
CAV2 caveolin 2
CCNE2 cyclin E2
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DYNLT3 dynein, light chain, Tctex-type 3
EGR3 early growth response 3
ETNK1 ethanolamine kinase 1
HACD2 3-hydroxyacyl-CoA dehydratase 2
HDGFRP3 hepatoma-derived growth factor, related protein 3
HSPH1 heat shock 105kDa/110kDa protein 1
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha
KIF14 kinesin family member 14
KIF23 kinesin family member 23
LDHB lactate dehydrogenase B
MET MET proto-oncogene, receptor tyrosine kinase
MSMB microseminoprotein, beta-
MYOF myoferlin
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
OPN3 opsin 3
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
RPS11 ribosomal protein S11
SAR1B secretion associated, Ras related GTPase 1B
SOAT1 sterol O-acyltransferase 1
SPAG1 sperm associated antigen 1
STK3 serine/threonine kinase 3
STOM stomatin
STS steroid sulfatase (microsomal), isozyme S
TIGAR TP53 induced glycolysis regulatory phosphatase
TOP2A topoisomerase (DNA) II alpha 170kDa
TSPYL5 TSPY-like 5
XBP1 X-box binding protein 1
XPO7 exportin 7