BRD-K54256913_MK-1775_A549_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

17 genes differentially expressed following the BRD-K54256913_MK-1775_A549_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ASNS asparagine synthetase (glutamine-hydrolyzing)
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
ERBB4 erb-b2 receptor tyrosine kinase 4
FRY furry homolog (Drosophila)
GADD45B growth arrest and DNA-damage-inducible, beta
GATA3 GATA binding protein 3
LDOC1 leucine zipper, down-regulated in cancer 1
MAN1A1 mannosidase, alpha, class 1A, member 1
NARFL nuclear prelamin A recognition factor-like
SLC38A1 solute carrier family 38, member 1
TRIM2 tripartite motif containing 2
UGDH UDP-glucose 6-dehydrogenase

decreased expression

Symbol Name
DKK1 dickkopf WNT signaling pathway inhibitor 1
FOLR1 folate receptor 1 (adult)
SRPX sushi-repeat containing protein, X-linked
TIMP4 TIMP metallopeptidase inhibitor 4