BRD-K54256913_MK-1775_A549_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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39 genes differentially expressed following the BRD-K54256913_MK-1775_A549_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BTG1 B-cell translocation gene 1, anti-proliferative
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CPE carboxypeptidase E
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
DPYSL3 dihydropyrimidinase-like 3
EED embryonic ectoderm development
FABP7 fatty acid binding protein 7, brain
GADD45B growth arrest and DNA-damage-inducible, beta
GBE1 glucan (1,4-alpha-), branching enzyme 1
GJA1 gap junction protein, alpha 1, 43kDa
HIST1H1C histone cluster 1, H1c
HOOK2 hook microtubule-tethering protein 2
HTRA1 HtrA serine peptidase 1
KANK1 KN motif and ankyrin repeat domains 1
LRRC15 leucine rich repeat containing 15
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
OSMR oncostatin M receptor
P3H2 prolyl 3-hydroxylase 2
PPAP2B phosphatidic acid phosphatase type 2B
RAB25 RAB25, member RAS oncogene family
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SORBS2 sorbin and SH3 domain containing 2
SULF1 sulfatase 1
TENM1 teneurin transmembrane protein 1
TGFA transforming growth factor, alpha
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
UGDH UDP-glucose 6-dehydrogenase
VTCN1 V-set domain containing T cell activation inhibitor 1
ZIC1 Zic family member 1

decreased expression

Symbol Name
CHPT1 choline phosphotransferase 1
IFI27 interferon, alpha-inducible protein 27
LAGE3 L antigen family, member 3
NEFL neurofilament, light polypeptide
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
PEBP1 phosphatidylethanolamine binding protein 1
ZNF586 zinc finger protein 586