BRD-K54256913_-666_SW620_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

107 genes differentially expressed following the BRD-K54256913_-666_SW620_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
APOD apolipoprotein D
ARMCX1 armadillo repeat containing, X-linked 1
AURKA aurora kinase A
BCHE butyrylcholinesterase
BIRC3 baculoviral IAP repeat containing 3
C1QB complement component 1, q subcomponent, B chain
CCL19 chemokine (C-C motif) ligand 19
CD14 CD14 molecule
CD163 CD163 molecule
CHRDL1 chordin-like 1
CPB1 carboxypeptidase B1 (tissue)
CTH cystathionine gamma-lyase
CXCL13 chemokine (C-X-C motif) ligand 13
CYBB cytochrome b-245, beta polypeptide
CYFIP2 cytoplasmic FMR1 interacting protein 2
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DCLK1 doublecortin-like kinase 1
EDNRB endothelin receptor type B
EIF5A eukaryotic translation initiation factor 5A
FLRT2 fibronectin leucine rich transmembrane protein 2
FOS FBJ murine osteosarcoma viral oncogene homolog
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GBP1 guanylate binding protein 1, interferon-inducible
GSPT2 G1 to S phase transition 2
HDGFRP3 hepatoma-derived growth factor, related protein 3
HOPX HOP homeobox
IL32 interleukin 32
KIF14 kinesin family member 14
KIF2C kinesin family member 2C
KRT14 keratin 14, type I
KRT17 keratin 17, type I
LAPTM4B lysosomal protein transmembrane 4 beta
LIMCH1 LIM and calponin homology domains 1
LONP2 lon peptidase 2, peroxisomal
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A
MTUS1 microtubule associated tumor suppressor 1
NNMT nicotinamide N-methyltransferase
NOV nephroblastoma overexpressed
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OLFM1 olfactomedin 1
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PBK PDZ binding kinase
PCSK1 proprotein convertase subtilisin/kexin type 1
PDE4B phosphodiesterase 4B, cAMP-specific
PLK1 polo-like kinase 1
PLXNC1 plexin C1
PMP22 peripheral myelin protein 22
RACGAP1 Rac GTPase activating protein 1
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RGS1 regulator of G-protein signaling 1
RUNX3 runt-related transcription factor 3
S100A13 S100 calcium binding protein A13
SARAF store-operated calcium entry-associated regulatory factor
SCN3A sodium channel, voltage gated, type III alpha subunit
SCRG1 stimulator of chondrogenesis 1
SMC1A structural maintenance of chromosomes 1A
SOX9 SRY (sex determining region Y)-box 9
TMEM45A transmembrane protein 45A
TNC tenascin C
VCAM1 vascular cell adhesion molecule 1
XPO7 exportin 7
XYLT1 xylosyltransferase I

decreased expression

Symbol Name
ADAM10 ADAM metallopeptidase domain 10
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
ADM adrenomedullin
AHSG alpha-2-HS-glycoprotein
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ANXA1 annexin A1
APLP2 amyloid beta (A4) precursor-like protein 2
APOA2 apolipoprotein A-II
CD99 CD99 molecule
CDV3 CDV3 homolog (mouse)
CLIC4 chloride intracellular channel 4
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DHRS9 dehydrogenase/reductase (SDR family) member 9
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FOSL1 FOS-like antigen 1
GCLC glutamate-cysteine ligase, catalytic subunit
GPC3 glypican 3
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IL1R2 interleukin 1 receptor, type II
KDM5D lysine (K)-specific demethylase 5D
LAMP1 lysosomal-associated membrane protein 1
LOC100505650 uncharacterized LOC100505650
LOXL1 lysyl oxidase-like 1
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
MSH6 mutS homolog 6
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2
MYH10 myosin, heavy chain 10, non-muscle
PDIA3 protein disulfide isomerase family A, member 3
PSEN1 presenilin 1
RGCC regulator of cell cycle
RGS5 regulator of G-protein signaling 5
SCGB2A1 secretoglobin, family 2A, member 1
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1
SFRP1 secreted frizzled-related protein 1
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SOX4 SRY (sex determining region Y)-box 4
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SRPR signal recognition particle receptor (docking protein)
TGFBI transforming growth factor, beta-induced, 68kDa
TRD T cell receptor delta locus
TRDV3 T cell receptor delta variable 3
TSPAN5 tetraspanin 5
TXNIP thioredoxin interacting protein
WNT5A wingless-type MMTV integration site family, member 5A