BRD-K53987533_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

24 genes differentially expressed following the BRD-K53987533_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ANXA1 annexin A1
CD59 CD59 molecule, complement regulatory protein
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
FXYD2 FXYD domain containing ion transport regulator 2
GBP2 guanylate binding protein 2, interferon-inducible
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMOX1 heme oxygenase 1
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
MMP7 matrix metallopeptidase 7
PON2 paraoxonase 2
RIN2 Ras and Rab interactor 2
RPL38 ribosomal protein L38
SRGN serglycin
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
ZNF331 zinc finger protein 331

decreased expression

Symbol Name
CNPY3 canopy FGF signaling regulator 3
CORO1A coronin, actin binding protein, 1A
ECM1 extracellular matrix protein 1
FGG fibrinogen gamma chain
GPR183 G protein-coupled receptor 183
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
RPS4Y1 ribosomal protein S4, Y-linked 1
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
TFF3 trefoil factor 3 (intestinal)