BRD-K53987533_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

36 genes differentially expressed following the BRD-K53987533_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
CA2 carbonic anhydrase II
CD40 CD40 molecule, TNF receptor superfamily member 5
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLC Charcot-Leyden crystal galectin
DDIT4 DNA-damage-inducible transcript 4
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4
STC1 stanniocalcin 1
STC2 stanniocalcin 2
WASF1 WAS protein family, member 1
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
ADI1 acireductone dioxygenase 1
CIT citron rho-interacting serine/threonine kinase
ENOPH1 enolase-phosphatase 1
EPCAM epithelial cell adhesion molecule
FOLR1 folate receptor 1 (adult)
GSTT1 glutathione S-transferase theta 1
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
KIF14 kinesin family member 14
KRAS Kirsten rat sarcoma viral oncogene homolog
LIMCH1 LIM and calponin homology domains 1
MED1 mediator complex subunit 1
NQO1 NAD(P)H dehydrogenase, quinone 1
NUP88 nucleoporin 88kDa
PDZD2 PDZ domain containing 2
PER3 period circadian clock 3
PLLP plasmolipin
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
SEH1L SEH1-like (S. cerevisiae)
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SPINK1 serine peptidase inhibitor, Kazal type 1
THBS1 thrombospondin 1
TJP2 tight junction protein 2
ZIC1 Zic family member 1