BRD-K53737926_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

49 genes differentially expressed following the BRD-K53737926_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSL3 acyl-CoA synthetase long-chain family member 3
ALDOC aldolase C, fructose-bisphosphate
CD9 CD9 molecule
CHGB chromogranin B
DDIT4 DNA-damage-inducible transcript 4
DFNA5 deafness, autosomal dominant 5
DHCR24 24-dehydrocholesterol reductase
DUSP4 dual specificity phosphatase 4
FADS1 fatty acid desaturase 1
FDPS farnesyl diphosphate synthase
FOSL1 FOS-like antigen 1
GBP1 guanylate binding protein 1, interferon-inducible
GBP2 guanylate binding protein 2, interferon-inducible
GCH1 GTP cyclohydrolase 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IDI1 isopentenyl-diphosphate delta isomerase 1
INSIG1 insulin induced gene 1
L1CAM L1 cell adhesion molecule
LDLR low density lipoprotein receptor
MSMO1 methylsterol monooxygenase 1
PDLIM1 PDZ and LIM domain 1
PF4 platelet factor 4
PLXNB2 plexin B2
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
RND3 Rho family GTPase 3
S100A2 S100 calcium binding protein A2
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SMAD3 SMAD family member 3
SQLE squalene epoxidase
SST somatostatin
TNS3 tensin 3
VEGFA vascular endothelial growth factor A
ZFP36L1 ZFP36 ring finger protein-like 1

decreased expression

Symbol Name
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
CA12 carbonic anhydrase XII
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CHMP4A charged multivesicular body protein 4A
ELF5 E74-like factor 5 (ets domain transcription factor)
FOXG1 forkhead box G1
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
LPL lipoprotein lipase
POSTN periostin, osteoblast specific factor
SELENBP1 selenium binding protein 1
SLPI secretory leukocyte peptidase inhibitor
TFF3 trefoil factor 3 (intestinal)
WFDC2 WAP four-disulfide core domain 2