BRD-K53638321_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

30 genes differentially expressed following the BRD-K53638321_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADD3 adducin 3 (gamma)
CFB complement factor B
CTH cystathionine gamma-lyase
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DHCR24 24-dehydrocholesterol reductase
FADS1 fatty acid desaturase 1
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
INSIG1 insulin induced gene 1
MSMO1 methylsterol monooxygenase 1
RPS11 ribosomal protein S11
S100A9 S100 calcium binding protein A9
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SPTSSA serine palmitoyltransferase, small subunit A
TNFAIP2 tumor necrosis factor, alpha-induced protein 2

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
AREG amphiregulin
EGFR epidermal growth factor receptor
IFI6 interferon, alpha-inducible protein 6
IGL immunoglobulin lambda locus
MACF1 microtubule-actin crosslinking factor 1
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
PEA15 phosphoprotein enriched in astrocytes 15
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
TSPAN12 tetraspanin 12
TUBB2A tubulin, beta 2A class IIa