BRD-K53592093_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

27 genes differentially expressed following the BRD-K53592093_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AMDHD2 amidohydrolase domain containing 2
FAM129A family with sequence similarity 129, member A
HOPX HOP homeobox
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
KRT23 keratin 23, type I
MAP7 microtubule-associated protein 7
PERP PERP, TP53 apoptosis effector
RRAS2 related RAS viral (r-ras) oncogene homolog 2
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A2 secretoglobin, family 2A, member 2
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SPON2 spondin 2, extracellular matrix protein
TCF4 transcription factor 4
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRG6 adhesion G protein-coupled receptor G6
CBR3 carbonyl reductase 3
DKK1 dickkopf WNT signaling pathway inhibitor 1
ERBB2 erb-b2 receptor tyrosine kinase 2
NAV2 neuron navigator 2
NQO1 NAD(P)H dehydrogenase, quinone 1
OAT ornithine aminotransferase
PEG10 paternally expressed 10
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
TNS3 tensin 3
TSPAN8 tetraspanin 8
TSPYL5 TSPY-like 5