BRD-K53579868_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

54 genes differentially expressed following the BRD-K53579868_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTR2 ARP2 actin-related protein 2 homolog (yeast)
ADM adrenomedullin
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C3 aldo-keto reductase family 1, member C3
BAX BCL2-associated X protein
CAV2 caveolin 2
CD44 CD44 molecule (Indian blood group)
COL11A1 collagen, type XI, alpha 1
COL9A3 collagen, type IX, alpha 3
FCGBP Fc fragment of IgG binding protein
GCLM glutamate-cysteine ligase, modifier subunit
GPX2 glutathione peroxidase 2
HMOX1 heme oxygenase 1
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16
KCNK1 potassium channel, two pore domain subfamily K, member 1
MET MET proto-oncogene, receptor tyrosine kinase
MT1F metallothionein 1F
NEBL nebulette
PDE4B phosphodiesterase 4B, cAMP-specific
PPAP2B phosphatidic acid phosphatase type 2B
PPP1R3C protein phosphatase 1, regulatory subunit 3C
RAB4A RAB4A, member RAS oncogene family
RGCC regulator of cell cycle
TGFA transforming growth factor, alpha
TXNRD1 thioredoxin reductase 1

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
ASRGL1 asparaginase like 1
BANK1 B-cell scaffold protein with ankyrin repeats 1
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CPM carboxypeptidase M
CTSH cathepsin H
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EVL Enah/Vasp-like
GUSBP3 glucuronidase, beta pseudogene 3
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IFI44L interferon-induced protein 44-like
LOC100272216 uncharacterized LOC100272216
MEIS1 Meis homeobox 1
N4BP2L2 NEDD4 binding protein 2-like 2
NPY neuropeptide Y
PEG3 paternally expressed 3
PLAT plasminogen activator, tissue
RBP1 retinol binding protein 1, cellular
RGL1 ral guanine nucleotide dissociation stimulator-like 1
SEPP1 selenoprotein P, plasma, 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
TACSTD2 tumor-associated calcium signal transducer 2
TIMP3 TIMP metallopeptidase inhibitor 3
TRAC T cell receptor alpha constant
TSPAN31 tetraspanin 31